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Enrofloxacin-d5 Sale

(Synonyms: 恩诺沙星-D5,BAY Vp 2674-d5; PD160788-d5) 目录号 : GC49101

An internal standard for the quantification of enrofloxacin

Enrofloxacin-d5 Chemical Structure

Cas No.:1173021-92-5

规格 价格 库存 购买数量
1 mg
¥918.00
现货
5 mg
¥2,651.00
现货
10 mg
¥4,385.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Enrofloxacin-d5 is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic.1 It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml).2 Enrofloxacin inhibits bacterial DNA gyrase.3 In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model of enteropathogenic E. coli-induced sepsis. Formulations containing enrofloxacin have been used in the treatment of veterinary bacterial infections.

1.Randall, L., Ridley, A., Lemma, F., et al.In vitro investigations into the use of antimicrobials in combination to maintain efficacy of fluoroquinolones in poultryRes. Vet. Sci.10847-53(2016) 2.Pereira, C.E.R., Resende, T.P., Vasquez, E., et al.In vitro antimicrobial activity against equine Lawsonia intracellularis strainsEquine Vet. J.51(5)665-668(2019) 3.Slate, A.R., Bandyopadhyay, S., Francis, K.P., et al.Efficacy of enrofloxacin in a mouse model of sepsisJ. Am. Assoc. Lab. Anim. Sci.53(4)381-386(2014)

Chemical Properties

Cas No. 1173021-92-5 SDF
别名 恩诺沙星-D5,BAY Vp 2674-d5; PD160788-d5
Canonical SMILES O=C1C2=CC(F)=C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])[2H])C=C2N(C4CC4)C=C1C(O)=O
分子式 C19H17D5FN3O3 分子量 364.4
溶解度 DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 1 mg/ml 储存条件 -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.7442 mL 13.7212 mL 27.4424 mL
5 mM 0.5488 mL 2.7442 mL 5.4885 mL
10 mM 0.2744 mL 1.3721 mL 2.7442 mL
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第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
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