(E)-Fenpyroximate
(Synonyms: 唑螨酯) 目录号 : GC46335A phenoxypyrazole acaricide
Cas No.:134098-61-6
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
(E)-Fenpyroximate is a phenoxypyrazole acaricide.1 It is lethal to mobile adult phytophagous mites of the genera Tetranychidae, Eriophyidae, and Tarsonemidae and inhibits molting at immature stages. (E)-Fenpyroximate reduces the number of eggs laid per female and is lethal to female A. swirskii predatory mites.2 It is also selectively lethal to worker over queen honey bees (LD50s = 30 and >1,620 μg/g, respectively).3 (E)-Fenpyroximate induces cell death in marine flounder (P. olivaceus) gill cells (IC50 = 800-1,250 nM) and is lethal to adult living flounder (LC50 = 28.84 nM in seawater).4
1.Konno, T., Kuriyama, K., and Hamaguchi, H.Fenpyroximate (NNI-850), a new acaricideBrighton Crop Protection Conference, Pests and Diseases171-78(1990) 2.Lopez, L., Smith, H.A., Hoy, M.A., et al.Acute toxicity and sublethal effects of fenpyroximate to Amblyseius swirskii (Acari: Phytoseiidae)J. Econ. Entomol.108(3)1047-1053(2015) 3.Dahlgren, L., Johnson, R.M., Siegfried, B.D., et al.Comparative toxicity of acaricides to honey bee (Hymenoptera: Apidae) workers and queensJ. Econ. Entomol.105(6)1895-1902(2012) 4.Na, N., Guo, H., Zhang, S., et al.In vitro and in vivo acute toxicity of fenpyroximate to flounder Paralichthys olivaceus and its gill cell line FGAquat. Toxicol.92(2)76-85(2009)
Cas No. | 134098-61-6 | SDF | |
别名 | 唑螨酯 | ||
Canonical SMILES | O=C(OC(C)(C)C)C1=CC=C(CO/N=C/C2=C(OC3=CC=CC=C3)N(C)N=C2C)C=C1 | ||
分子式 | C24H27N3O4 | 分子量 | 421.5 |
溶解度 | Chloroform: Slightly soluble,Methanol: Slightly soluble | 储存条件 | Store at -20°C |
General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。 为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。 |
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Shipping Condition | 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。 |
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 2.3725 mL | 11.8624 mL | 23.7248 mL |
5 mM | 0.4745 mL | 2.3725 mL | 4.745 mL |
10 mM | 0.2372 mL | 1.1862 mL | 2.3725 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Evaluation of pesticide residues in commercial Swiss beeswax collected in 2019 using ultra-high performance liquid chromatographic analysis
Environ Sci Pollut Res Int 2022 May;29(21):32054-32064.PMID:35018599DOI:PMC9054900
The aim of this study was to determine residue levels of pesticides in Swiss commercial beeswax. Foundation samples were collected in 2019 from nine commercial manufacturers for analysis of 21 pesticides using ultra-high performance liquid chromatography. Individual samples showed the variability and residue ranges and pooled samples represented the average annual residue values of the Swiss production. In total, 17 pesticides were identified and 13 pesticides were quantified. They included 13 acaricides and/or insecticides, two fungicides as well as a synergist and a repellent. The means calculated from individual samples were similar to the average annual residue values for most tested pesticides. Mean values of 401, 236, 106 and 3 μg·kg-1 were obtained for the beekeeping-associated contaminants coumaphos, tau-fluvalinate, bromopropylate and N-(2,4-Dimethylphenyl)-formamide (DMF; breakdown product of amitraz), respectively. For the other pesticides, the mean values were 203 μg·kg-1 (synergist piperonyl butoxide), 120 μg·kg-1 (repellent N,N-Diethyl-3-methylbenzamide, DEET), 19 μg·kg-1 (chlorfenvinphos) and 4 μg·kg-1 ((E)-Fenpyroximate), while the means for acrinathrin, azoxystrobin, bendiocarb, boscalid, chlorpyrifos, flumethrin, permethrin, propoxur and thiacloprid were below the limit of quantification (< LOQ). Individual samples contained from seven to 14 pesticides. The ranges of values for coumaphos and piperonyl butoxide (from 14 to 4270 μg·kg-1; from 6 to 1555 μg·kg-1, respectively) were larger as compared to the ranges of values for DEET and tau-fluvalinate (from < LOQ to 585 μg·kg-1; from 16 to 572 μg·kg-1, respectively). In conclusion, the most prominent contaminants were the pesticides coumaphos and tau-fluvalinate, which are both acaricides with previous authorization for beekeeping in Switzerland, followed by piperonyl butoxide, a synergist to enhance the effect of insecticides.