DLL4 Human
目录号 : GP26281DLL4 Human Recombinant produced in HEK293 is a single glycosylated polypeptide chain containing 504 amino acids (27-529 a
Sample solution is provided at 25 µL, 10mM.
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DLL4 Human Recombinant produced in HEK293 is a single glycosylated polypeptide chain containing 504 amino acids (27-529 a.a) and having a molecular mass of 55.1kDa. DLL4 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | HEK293. |
| Phycical Appearance | Sterilefiltered colorless solution. | Shipping Condition | withIcePacks |
| Synonyms | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, delta like canonical Notch ligand 4, AOS6, hdelta2. | ||
| Amino Acid Sequence | SGVFQLQLQE FINERGVLAS GRPCEPGCRT FFRVCLKHFQ AVVSPGPCTF GTVSTPVLGT NSFAVRDDSS GGGRNPLQLP FNFTWPGTFS LIIEAWHAPG DDLRPEALPP DALISKIAIQ GSLAVGQNWL LDEQTSTLTR LRYSYRVICS DNYYGDNCSR LCKKRNDHFG HYVCQPDGNL SCLPGWTGEY CQQPICLSGC HEQNGYCSKP AECLCRPGWQ GRLCNECIPH NGCRHGTCST PWQCTCDEGW GGLFCDQDLN YCTHHSPCKN GATCSNSGQR SYTCTCRPGY TGVDCELELS ECDSNPCRNG GSCKDQEDGY HCLCPPGYYG LHCEHSTLSC ADSPCFNGGS CRERNQGANY ACECPPNFTG SNCEKKVDRC TSNPCANGGQ CLNRGPSRMC RCRPGFTGTY CELHVSDCAR NPCAHGGTCH DLENGLMCTC PAGFSGRRCE VRTSIDACAS SPCFNRATCY TDLSTDTFVC NCPYGFVGSR CEFPVGLPHH HHHH. | ||
| Stability | Store at 4буC if entire vial will be used within 2-4 weeks.Store, frozen at -20буC for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | DLL4 protein solution (0.25mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol. | ||
Delta-Like4 or DLL4 is implicated in the Notch signaling transduction as Notch ligand. DLL4 down regulates endothelial cell proliferation, migration and angiogenic sprouting. DLL4 is crucial for retinal progenitor proliferation &furthermore required for suppressing rod fates in late retinal progenitors & for proper generation of other retinal cell types. Also, at some stages in the spinal cord neurogenesis, DLL4 inhibits V2a interneuron fate.
Store at 4буC if entire vial will be used within 2-4 weeks.Store, frozen at -20буC for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.