Deltamethrin-d5
(Synonyms: Decamethrin-d5) 目录号 : GC63475
An internal standard for the quantification of deltamethrin
Cas No.:2140301-99-9
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Deltamethrin-d5 is intended for use as an internal standard for the quantification of deltamethrin by GC- or LC-MS. Deltamethrin is a type II pyrethroid insecticide and a modulator of voltage-gated sodium channels (Nav).1 It activates Nav1.8 channels and induces a tail current delay in Xenopus oocytes expressing the rat channel when used at a concentration of 10 ?M. Deltamethrin induces mortality in A. sinensis (LC50 = 4.522 ppm) and T. urticae (LC50 = 0.06 g/L).2,3 It decreases sperm count, motility, and viability and increases the percentage of morphologically abnormal sperm in rats when administered at a dose of 5 mg/kg.4 Formulations containing deltamethrin have been used as domestic and agricultural insecticides.
1.Choi, J.S., and Soderlund, D.M.Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Nav1.8 sodium channels expressed in Xenopus oocytesToxicol. Appl. Pharmacol.211(3)233-244(2006) 2.Chang, K.-S., Yoo, D.-H., Shin, E.-H., et al.Susceptibility and resistance of field populations of Anopheles sinensis (Diptera: Culicidae) collected from Paju to 13 insecticidesOsong Public Health Res. Perspect.4(2)76-80(2013) 3.Penman, D.R., Chapman, R.B., and Bowie, M.H.Direct toxicity and repellent activity of pyrethroids against Tetranychus urticae (Acari: Tetranychidae)J. Econ. Entomol.79(5)1183-1187(1986) 4.Abdallah, F.B., Slima, A.B., Dammak, I., et al.Comparative effects of dimethoate and deltamethrin on reproductive system in male miceAndrologia42(3)182-186(2010)
| Cas No. | 2140301-99-9 | SDF | |
| 别名 | Decamethrin-d5 | ||
| 分子式 | C22H14D5Br2NO3 | 分子量 | 510.23 |
| 溶解度 | 储存条件 | Store at -20°C | |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.9599 mL | 9.7995 mL | 19.599 mL |
| 5 mM | 0.392 mL | 1.9599 mL | 3.9198 mL |
| 10 mM | 0.196 mL | 0.98 mL | 1.9599 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。