DCT Human
目录号 : GP21543Dopachrome Tautomerase Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90% as determined by SDS-PAGE. | Source | Sf9 Insect cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | L-dopachrome tautomerase (EC:5.3.3.12); DCT; DT; L-dopachromeDelta-isomerase Tyrosinase-related protein2; TRP-2; TRP2; TYRP2. | ||
| Amino Acid Sequence | QFPRVCMTVD SLVNKECCPRLGAESANVCG SQQGRGQCTE VRADTRPWSG PYILRNQDDR ELWPRKFFHR TCKCTGNFAG YNCGDCKFGW TGPNCERKKP PVIRQNIHSL SPQEREQFLG ALDLAKKRVH PDYVITTQHW LGLLGPNGTQ PQFANCSVYDFFVWLHYYSV RDTLLGPGRP YRAIDFSHQG PAFVTWHRYH LLCLERDLQR LIGNESFALP YWNFATGRNECDVCTDQLFG AARPDDPTLI SRNSRFSSWE TVCDSLDDYN HLVTLCNGTY EGLLRRNQMG RNSMKLPTLK DIRDCLSLQK FDNPPFFQNS TFSFRNALEG FDKADGTLDS QVMSLHNLVH SFLNGTNALP HSAANDPIFVVLHSFTDAIF DEWMKRFNPP ADAWPQELAP IGHNRMYNMV PFFPPVTNEE LFLTSDQLGY SYAIDLPVSVEETPGWPTTH HHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | STK3 protein solution (0.25mg/ml) containing PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
Dopachrome Tautomerase also known as DCT,belongs to the tyrosinase family. DCT takes a significant part in the synthesisof the melanin pigment including tyrosinase (Tyr), tyrosinase-related protein 1(Tyrp1). Which are highly involved in eumelanin synthesis. The change among theeumelanin and the pheomelanin pathways is assumed to depend on the presence ofcysteine. Hence, in the lack of cysteine, dopaquinone, the product oftyrosinase action, is transformed to cyclodopa (leucodopachrome) and afterwardsto dopachrome (and DOPA).
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.