CXCL4 Variant 1 Human
目录号 : GP21199Platelet Factor-4 Variant 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 95.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered white lyophilized powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | CXCL4; PF-4; PF4; Iroplact; Oncostatin-A; SCYB4; MGC138298. | ||
| Amino Acid Sequence | MHHHHHHEAE EDGDLQCLCV KTTSQVRPRH ITSLEVIKAG PHCPTAQLIA TLKNGRKICL DLQALLYKKI IKEHLES. | ||
| Solubility | It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C . Please prevent freeze-thaw cycles. | ||
| Formulation | The protein was lyophilized without additives. | ||
Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets . Its major physiologic role appears to be neutralization of molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy.
Human CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C . Please prevent freeze-thaw cycles.