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CFB Human, Sf9

目录号 : GP23132

Complement Factor B Human Recombinant, Sf9

CFB Human, Sf9 Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

CFB Human Recombinant produced in Sf9 Baculovirus cells isa single, glycosylated polypeptide chain containing 245 amino acids (26-259a.a.)and having a molecular mass of 27.3kDa (Molecular size on SDS-PAGE will appearat approximately 28-40 kDa). CFB is expressed with a 11 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Sf9, Baculovirus cells.
Phycical Appearance Sterile Filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms CFB; AHUS4; ARMD14; BF; BFD; CFAB; CFBD; FB; FBI12; GBG;H2-Bf; PBF2; Complement Factor B; B-Factor; Properdin; Properdin Factor B;C3/C5 Convertase; EC 3.4.21.47; PBF2;Glycine-Rich Beta-Glycoprotein;Glycine-Rich Beta Glycoprotein; C3 Proaccelerator; C3 Proactivator ; EC 3.4.2;FBI12; H2-Bf.
Amino Acid Sequence ADPEFTPWSLARPQGSCSLE GVEIKGGSFR LLQEGQALEY VCPSGFYPYP VQTRTCRSTG SWSTLKTQDQ KTVRKAECRAIHCPRPHDFE NGEYWPRSPY YNVSDEISFH CYDGYTLRGS ANRTCQVNGR WSGQTAICDN GAGYCSNPGIPIGTRKVGSQ YRLEDSVTYH CSRGLTLRGS QRRTCQEGGS WSGTEPSCQD SFMYDTPQEV AEAFLSSLTETIEGVDAEDG HGPGEQQKRH HHHHH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CFB protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol.

Introduction

Complement Factor B, also known as CFB, encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also, Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.