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CFB-a Human

目录号 : GP26250

CFB-a Human produced in Human Plasma having a molecular mass of 33 kDa

CFB-a Human Chemical Structure

规格 价格 库存 购买数量
10μg
¥5,390.00
现货
50μg
¥14,630.00
现货
100μg
¥23,100.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

CFB-a Human produced in Human Plasma having a molecular mass of 33 kDa.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Human Plasma.
Phycical Appearance Sterile filtered solution. Shipping Condition withIcePacks
Synonyms Complement factor B (EC:3.4.21.47), C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, Complement Factor B, BFD, AHUS4, BF, BFD, CFAB, FB, FBI12, H2-Bf.
Stability CFB-a Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CFB-a solution (1mg/ml) contains Phosphate-buffered saline, pH 7.3.

Introduction

Complement Factor B, also known as CFB, encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also, Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

Stability

CFB-a Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.