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CD47 Human, IgG-His

目录号 : GP23026

CD47 Human Recombinant, IgG-His Tag

CD47 Human, IgG-His Chemical Structure

规格 价格 库存 购买数量
2μg
¥840.00
5-10工作日
10μg
¥2,030.00
5-10工作日
1mg
¥72,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

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产品描述

CD47 HumanRecombinant produced in Sf9 Insect cell is a single, non-glycosylatedpolypeptide chain containing 362 amino acids (19-141aa.a) and having amolecular mass of 40.9kDa (Migrates at 40-57kDa on SDS-PAGE under reducingconditions).CD47 is fused to a 239 amino acid hIgG-His-tag atC-terminus & purified by proprietary chromatographic techniques.

Product Data

Purity Greater than 95.0% as determined by SDS-PAGE. Source Sf9, Insect cells.
Phycical Appearance Sterile filtered colorless solution. Shipping Condition Shipped with Ice Packs.
Synonyms CD47Molecule; Antigenic Surface Determinant Protein OA3; CD47 Antigen (Rh-RelatedAntigen; Integrin-Associated Signal Transducer); Antigen Identified byMonoclonal; Antibody 1D8; Integrin Associated Protein; Integrin-AssociatedProtein; Rh-Related; Antigen; CD47 Glycoprotein; MER6; IAP; Integrin-AssociatedSignal Transducer; Leukocyte Surface Antigen CD47; CD47 Antigen; Protein MER6; OA3.
Amino Acid Sequence QLLFNKTKSVEFTFCNDTVV IPCFVTNMEA QNTTEVYVKW KFKGRDIYTF DGALNKSTVP TDFSSAKIEV SQLLKGDASLKMDKSDAVSH TGNYTCEVTE LTREGETIIE LKYRVVSWFS PNELEPKSCD KTHTCPPCPA PELLGGPSVFLFPPKPKDTL MISRTPEVTC VVVDVSHEDPEVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKCKVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNYKTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation CD47 proteinsolution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10%glycerol.

Introduction

CD47, functions in cell adhesions by performing as an adhesion receptor for THBS1 on platelets, furthermore CD47 plays a role in the modulation of integrins. In addition, CD47 takes a vital part in memory formation as well as synaptic plasticity in the hippocampus. Receptor for SIRPA avoids maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 prevents premature elimination of red blood cells, and it is also implicated in membrane permeability changes induced following virus infection.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.