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Mastoparan Sale

(Synonyms: 黄峰毒素) 目录号 : GC12692

A mast cell degranulating peptide

Mastoparan Chemical Structure

Cas No.:72093-21-1

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1mg
¥891.00
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5mg
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10mg
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25mg
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

Mastoparan has an amphiphilic nature and is reported to exert a variety of pharmacological and biochemical effects. Mastoparan induces exocytosis of hormones from anterior pituitary cells. Mastoparan stimulation of prolactin secretion is dose-dependent, time-dependent, reversible and required the presence of calcium. Mastoparan causes translocation of protein kinase C activity from a soluble to a membrane-attached form. Mastoparan is able to increase the intracellular Ca2+ concentration in Fura-2-loaded individual lactotrophs. Mastoparan is also able to interact with GTP-bindmg proteins. Thus, Mastoparan has been shown to facilitate exchange of nucleotides and to stimulate GTPase activity on G-proteins. It has therefore been proposed that the cellular effects of Mastoparan are due to an ability to mimic G-protein-linked agonist-liganded receptors[1].

References:
[1]. Mau SE, et al. Mastoparan, a wasp venom peptide, stimulates release of prolactin from cultured rat anterior pituitary cells. J Endocrinol. 1994 Jul;142(1):9-18.

Chemical Properties

Cas No. 72093-21-1 SDF
别名 黄峰毒素
化学名 (S,Z)-2-((Z)-((2S,3S)-2-amino-1-hydroxy-3-methylpentylidene)amino)-N'1-((4S,5Z,7S,8Z,10S,11Z,13S,14Z,16S,17Z,19S,20Z,22S,23Z,25S,26Z,28S,29Z,31S,32Z,34S,35Z,37S)-10,13,34-tris(4-aminobutyl)-7-((S)-sec-butyl)-6,9,12,15,18,21,24,27,30,33,36-undecahydroxy-4-
Canonical SMILES CC[C@]([C@@](N)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](C(O)=N)([H])CC(C)C)([H])[C@@](CC)([H])C)([H])CCCCN)([
分子式 C70H131N19O15 分子量 1479
溶解度 Soluble to 2.60 mg/ml in sterile water 储存条件 Desiccate at -20°C
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.6761 mL 3.3807 mL 6.7613 mL
5 mM 0.1352 mL 0.6761 mL 1.3523 mL
10 mM 0.0676 mL 0.3381 mL 0.6761 mL
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