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TLR(Toll样受体)

TLR (Toll-like receptor) is a family of receptors that expressed on immune cells including B lymphoctes, macrophages and mast cells. Ir identifies pathogen-associated molecular patterns and mediate the cytokines productions for activation of innate immunity.

  1. Cat.No. 产品名称 Information
  2. GC66870 β-D-Glucan
  3. GC38728 1V209 1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
  4. GC63485 Afimetoran
  5. GC66396 Agatolimod
  6. GC32057 AN-3485
  7. GC62334 AT791
  8. GN10627 Atractylenolide I A sesquiterpene with diverse biological activities
  9. GC65283 AXC-715 trihydrochloride
  10. GC62488 AZD8848
  11. GC16345 Bropirimine An immunomodulator with diverse biological activities
  12. GC33820 C29

    C29 是一种 Toll 样受体 2 (TLR2) 抑制剂。

  13. GC60694 Chitohexaose hexahydrochloride
  14. GC60700 Chloroquine D5 An internal standard for the quantification of chloroquine
  15. GC10295 Chloroquine diphosphate

    An aminoquinoline

  16. GC50356 CL 075 CL 075 (3M002) 是一种具有免疫调节特性的选择性 TLR8 激动剂。
  17. GC64526 CL097
  18. GC65124 CL097 hydrochloride
  19. GC14254 CU CPT 22 An antagonist of TLR1/TLR2
  20. GC11461 CU CPT 4a A TLR3 antagonist
  21. GC47127 CU-115 A TLR8 antagonist
  22. GC25314 CU-CPD107 CU-CPD107 is a selective, dual-activity small-molecule which demonstrated differential activity against the TLR8 agonists and ssRNA ligands. In the presence of R848, CU-CPD107 acts as a TLR8 signaling inhibitor (IC50=13.7 μM). In the presence of ssRNA, CU-CPD107 shows synergistic agonist activities, while CU-CPD107 alone is unable to influence TLR8 signaling.
  23. GC31745 CU-CPT-9a A TLR8 antagonist
  24. GC31729 CU-CPT-9b (TLR8-specific antagonist 1) A TLR8 antagonist
  25. GC33834 CU-CPT17e
  26. GC18306 CU-CPT8m A TLR8 antagonist
  27. GC39285 CU-T12-9 An agonist of TLR1/2
  28. GC68432 DB-3-291
  29. GC39372 Desethyl chloroquine diphosphate
  30. GC47194 Desethylchloroquine An active metabolite of chloroquine
  31. GC38907 DSR-6434 A TLR7 agonist
  32. GC33900 E6446 E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro.
  33. GC33828 E6446 dihydrochloride (E-6446 dihydrochloride) E6446 dihydrochloride is a specific Toll-like receptor 9 inhibitor.
  34. GC62489 Enpatoran
  35. GC62471 Enpatoran hydrochloride
  36. GC18761 FSL-1 A lipopeptide agonist of TLR2/TLR6
  37. GC60860 FSL-1 TFA

    FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.

  38. GC14864 Gardiquimod A selective agonist of human TLR7
  39. GC33910 Gardiquimod trifluoroacetate A selective agonist of human TLR7
  40. GC12555 GS-9620 A TLR7 agonist
  41. GC12544 Hydroxychloroquine Sulfate

    An aminoquinolone with antimalarial and anti-inflammatory activities

  42. GC65365 IAXO-102 A glycolipid TLR4 antagonist
  43. GC16407 Imiquimod

    A TLR7 agonist

  44. GC10712 Imiquimod hydrochloride A TLR7 agonist
  45. GC12645 Imiquimod maleate A TLR7 agonist
  46. GC39134 Isofraxidin Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
  47. GC64417 L48H37
  48. GC66478 LHC-165
  49. GC65924 Lipopolysaccharides
  50. GC50241 M62812 TLR-4 inhibitor
  51. GC31776 MD2-IN-1 MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD value of 189?μM.

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