TLR(Toll样受体)
TLR (Toll-like receptor) is a family of receptors that expressed on immune cells including B lymphoctes, macrophages and mast cells. Ir identifies pathogen-associated molecular patterns and mediate the cytokines productions for activation of innate immunity.
- Cat.No. 产品名称 Information
-
GC66870
β-D-Glucan
-
GC38728
1V209
1V209 (T7, TLR7 agonist T7) is an agonist of Toll-like receptor 7 (TLR7) with anti-tumor effects. 1V209 can be used as vaccine adjuvants, enhances antigen specific humoral and cellular immune responses.
-
GC63485
Afimetoran
-
GC66396
Agatolimod
-
GC32057
AN-3485
-
GC62334
AT791
-
GN10627
Atractylenolide I
A sesquiterpene with diverse biological activities
-
GC65283
AXC-715 trihydrochloride
-
GC62488
AZD8848
-
GC16345
Bropirimine
An immunomodulator with diverse biological activities
-
GC33820
C29
C29 是一种 Toll 样受体 2 (TLR2) 抑制剂。
-
GC60694
Chitohexaose hexahydrochloride
-
GC60700
Chloroquine D5
An internal standard for the quantification of chloroquine
-
GC10295
Chloroquine diphosphate
An aminoquinoline
-
GC50356
CL 075
CL 075 (3M002) 是一种具有免疫调节特性的选择性 TLR8 激动剂。
-
GC64526
CL097
-
GC65124
CL097 hydrochloride
-
GC14254
CU CPT 22
An antagonist of TLR1/TLR2
-
GC11461
CU CPT 4a
A TLR3 antagonist
-
GC47127
CU-115
A TLR8 antagonist
-
GC25314
CU-CPD107
CU-CPD107 is a selective, dual-activity small-molecule which demonstrated differential activity against the TLR8 agonists and ssRNA ligands. In the presence of R848, CU-CPD107 acts as a TLR8 signaling inhibitor (IC50=13.7 μM). In the presence of ssRNA, CU-CPD107 shows synergistic agonist activities, while CU-CPD107 alone is unable to influence TLR8 signaling.
-
GC31745
CU-CPT-9a
A TLR8 antagonist
-
GC31729
CU-CPT-9b (TLR8-specific antagonist 1)
A TLR8 antagonist
-
GC33834
CU-CPT17e
-
GC18306
CU-CPT8m
A TLR8 antagonist
-
GC39285
CU-T12-9
An agonist of TLR1/2
-
GC68432
DB-3-291
-
GC39372
Desethyl chloroquine diphosphate
-
GC47194
Desethylchloroquine
An active metabolite of chloroquine
-
GC38907
DSR-6434
A TLR7 agonist
-
GC33900
E6446
E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro.
-
GC33828
E6446 dihydrochloride (E-6446 dihydrochloride)
E6446 dihydrochloride is a specific Toll-like receptor 9 inhibitor.
-
GC62489
Enpatoran
-
GC62471
Enpatoran hydrochloride
-
GC18761
FSL-1
A lipopeptide agonist of TLR2/TLR6
-
GC60860
FSL-1 TFA
FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
-
GC14864
Gardiquimod
A selective agonist of human TLR7
-
GC33910
Gardiquimod trifluoroacetate
A selective agonist of human TLR7
-
GC12555
GS-9620
A TLR7 agonist
-
GC12544
Hydroxychloroquine Sulfate
An aminoquinolone with antimalarial and anti-inflammatory activities
-
GC65365
IAXO-102
A glycolipid TLR4 antagonist
-
GC16407
Imiquimod
A TLR7 agonist
-
GC10712
Imiquimod hydrochloride
A TLR7 agonist
-
GC12645
Imiquimod maleate
A TLR7 agonist
-
GC39134
Isofraxidin
Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
-
GC64417
L48H37
-
GC66478
LHC-165
-
GC65924
Lipopolysaccharides
-
GC50241
M62812
TLR-4 inhibitor
-
GC31776
MD2-IN-1
MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD value of 189?μM.