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(+)-Camphor (D-(+)-Camphor) Sale

(Synonyms: (+)-樟脑; D-(+)-Camphor; (1R)-(+)-Camphor) 目录号 : GC33515

A terpene with diverse biological activities

(+)-Camphor (D-(+)-Camphor) Chemical Structure

Cas No.:464-49-3

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10mM (in 1mL DMSO)
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1g
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产品描述

(1R)-(+)-Camphor is a terpene that has been found in C. sativa, C. indica, and C. sativa/C. indica hybrid strains as well as the essential oils from a variety of herbs including rosemary, lavender, and sage and has diverse biological activities.1,2,3,4,5,6 It inhibits norepinephrine secretion and cytosolic calcium and sodium increases induced by the nicotinic acetylcholine receptor (nAChR) agonist 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) in chromaffin cells (IC50s = 70, 88, and 19 μM, respectively).2 (1R)-(+)-Camphor (65-260 μM) induces proliferation of and increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in human primary dermal fibroblasts.3 In vivo, (1R)-(+)-camphor increases expression of collagen IA, collagen IIIA, collagen IVA, and elastin in skin in UV-exposed mice when administered at doses of 26 and 55 mM in drinking water post UV-exposure. It reduces cough frequency in citric acid-challenged guinea pigs.4 (1R)-(+)-Camphor is insecticidal, reducing digging activity and inducing mortality of fire ant workers.5 It has also been used as a building block in the synthesis of cannabinergic ligands.6

1.Elzinga, S., Fischedick, J., Podkolinski, R., et al.Cannabinoids and terpenes as chemotaxonomic markers in CannabisNat. Prod. Chem. Res.3(4)181(2015) 2.Park, T.-J., Seo, H.-K., Kang, B.-J., et al.Noncompetitive inhibition by camphor of nicotinic acetylcholine receptorsBiochem. Pharmacol.61(7)787-793(2001) 3.Tran, T.A., Ho, M.T., Song, Y.W., et al.Camphor induces proliferative and anti-senescence activities in human primary dermal fibroblasts and inhibits UV-induced wrinkle formation in mouse skinPhytother. Res.29(12)1917-1925(2015) 4.Laude, E.A., Morice, A.H., and Grattan, T.J.The antitussive effects of menthol, camphor and cineole in conscious guinea-pigsPulm. Pharmacol.7(3)179-184(1994) 5.Zhang, N., Tang, L., Hu, W., et al.Insecticidal, fumigant, and repellent activities of sweet wormwood oil and its individual components against red imported fire ant workers (Hymenoptera: Formicidae)J. Insect Sci.14(1)pii:241(2014) 6.Lu, D., Guo, J., Duclos, R.I., Jr., et al.Bornyl- and isobornyl-Δ8-tetrahydrocannabinols: A novel class of cannabinergic ligandsJ. Med. Chem.51(20)6393-6399(2008)

Chemical Properties

Cas No. 464-49-3 SDF
别名 (+)-樟脑; D-(+)-Camphor; (1R)-(+)-Camphor
Canonical SMILES CC1(C)[C@@]2(C)CC[C@@H]1CC2=O
分子式 C10H16O 分子量 152.23
溶解度 DMSO : ≥ 50 mg/mL (328.45 mM) 储存条件 Store at -20°C
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1 mg 5 mg 10 mg
1 mM 6.569 mL 32.845 mL 65.6901 mL
5 mM 1.3138 mL 6.569 mL 13.138 mL
10 mM 0.6569 mL 3.2845 mL 6.569 mL
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