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Calcium D-Glucarate (hydrate) Sale

(Synonyms: 葡萄糖二酸鈣) 目录号 : GC47020

The calcium salt form of D-glucaric acid

Calcium D-Glucarate (hydrate) Chemical Structure

Cas No.:5793-89-5

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25 g
¥514.00
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50 g
¥976.00
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100 g
¥1,645.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Calcium D-glucarate is the calcium salt form of D-glucaric acid.1 D-Glucaric acid is an end product of D-glucuronic acid metabolism in mammals that has also been found in fruits and vegetables and has anticancer activity.2 It is produced by the oxidation of D-glucuronic acid and is a precursor in the biosynthesis of the β-glucuronidase inhibitor D-glucaro-1,4-lactone in vivo.1 Dietary administration of calcium D-glucarate (10% w/w) reduces tumor growth in a rat model of mammary tumorigenesis induced by 7,12-dimethylbenz[a]anthracene (DMBA).3 Urinary D-glucaric acid levels have been used as a marker for xenobiotic-induced phase II metabolism in patients with rheumatoid arthritis or individuals exposed to environmental toxicants.4,5

1.Walaszek, Z.Potential use of D-glucaric acid derivatives in cancer preventionCancer Lett.54(1-2)(1990) 2.ZÓ?taszek, R., Hanausek, M., Kiliańska, Z., et al.The biological role of D-glucaric acid and its derivatives: potential use in medicinePostepy. Hig. Med. Dosw. (Online)62451-462(2008) 3.Walaszek, Z., Hanausek-Walaszek, M., Minton, J.P., et al.Dietary glucarate as anti-promoter of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesisCarcinogenesis7(9)1463-1466(1986) 4.Addyman, R., Beyeler, C., Astbury, C., et al.Urinary glucaric acid excretion in rheumatoid arthritis: influence of disease activity and disease modifying drugsAnn. Rheum. Dis.55(7)478-481(1996) 5.IdÉo, G., Bellati, G., Bellohuono, A., et al.Urinary D-glucaric acid excretion in the Seveso area, polluted by tetrachloro-dibenzo-p-dioxin (TCDD): five years of experienceEnviron. Health Perspect.60151-157(1976)

Chemical Properties

Cas No. 5793-89-5 SDF
别名 葡萄糖二酸鈣
Canonical SMILES [O-]C([C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O)=O.[Ca+2].O.O.O.O
分子式 C6H8O8.Ca [4H2O] 分子量 320.3
溶解度 Methanol: slightly soluble,PBS (pH 7.2): slightly soluble 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

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1 mg 5 mg 10 mg
1 mM 3.1221 mL 15.6104 mL 31.2207 mL
5 mM 0.6244 mL 3.1221 mL 6.2441 mL
10 mM 0.3122 mL 1.561 mL 3.1221 mL
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