C1QTNF3 Human
目录号 : GP22931Complement C1q Tumor Necrosis Factor-Related Protein 3 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | The purity of C1QTNF3 is greater than 95% as determined by SDS PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Shipping Condition | Shipped at Room temp. | |
| Synonyms | Complement C1q tumor necrosis factor-related protein 3; Secretory protein CORS26; C1QTNF3; CTRP3; Cors; Corcs; CORS26; FLJ37576; Cartducin. | ||
| Amino Acid Sequence | MKHHHHHHAS QDEYMESPQT GGLPPDCSKC CHGDYSFRGY QGPPGPPGPP GIPGNHGNNG NNGATGHEGA KGEKGDKGDL GPRGERGQHG PKGEKGYPGI PPELQIAFMA SLATHFSNQN SGIIFSSVET NIGNFFDVMT GRFGAPVSGV YFFTFSMMKH EDVEEVYVYL MHNGNTVFSM YSYEMKGKSD TSSNHAVLKL AKGDEVWLRM GNGALHGDHQ RFSTFAGFLLFETK. | ||
| Solubility | It is recommended to add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10µg/ml. In higher concentrations the solubility of the protein is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. | ||
| Stability | Store lyophilized C1QTNF3 at -20°C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C . | ||
| Formulation | Human C1QTNF3 was filtered (0.4µm) and lyophilized in 0.5 mg/ml in 0.05M Acetate buffer pH4. | ||
C1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells.
Store lyophilized C1QTNF3 at -20°C . Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C .