Home>>Peptides>>β-Amyloid 1-28 (Amyloid β-Protein (1-28))

β-Amyloid 1-28 (Amyloid β-Protein (1-28)) Sale

(Synonyms: Amyloid β-Protein (1-28)) 目录号 : GC31171

β-Amyloid 1-28 (Amyloid β-Protein (1-28)) 是 β-Amyloid 蛋白片段,参与金属结合。

β-Amyloid 1-28 (Amyloid β-Protein (1-28)) Chemical Structure

Cas No.:109770-29-8

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1mg
¥1,428.00
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5mg
¥5,712.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

β-Amyloid (1-28) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab-Cu2+ interaction[1]. Copper binds to β-Amyloid (1-28) at pH 7.4 with an affinity of Ka10 7 M-1[2].

[1]. Kowalik-Jankowska T, et al. Coordination abilities of the 1-16 and 1-28 fragments of beta-amyloid peptide towards copper(II) ions: a combined potentiometric and spectroscopic study. J Inorg Biochem. 2003 Jul 1;95(4):270-82. [2]. Syme CD, et al. Copper binding to the amyloid-beta (Abeta) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Abeta-(1-28): insights from a range of complementary spectroscopic techniques. J Biol Chem. 2004 Apr 30;279(18):18169-77.

Chemical Properties

Cas No. 109770-29-8 SDF
别名 Amyloid β-Protein (1-28)
Canonical SMILES Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys
分子式 C145H209N41O46 分子量 3262.51
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.3065 mL 1.5326 mL 3.0651 mL
5 mM 0.0613 mL 0.3065 mL 0.613 mL
10 mM 0.0307 mL 0.1533 mL 0.3065 mL
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