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APOBEC4 Human

目录号 : GP22745

Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 4 Human Recombinant

APOBEC4 Human Chemical Structure

规格 价格 库存 购买数量
5μg
¥840.00
5-10工作日
20μg
¥2,030.00
5-10工作日
1mg
¥37,800.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

APOBEC4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 390 amino acids (1-367aa) and having a molecular mass of 44kDa.

Product Data

Purity Greater than 85% as determined by SDS-PAGE. Source Escherichia Coli.
Phycical Appearance Sterile Filtered clear solution. Shipping Condition Shipped with Ice Packs.
Synonyms Apolipoprotein B MRNA Editing Enzyme; CatalyticPolypeptide-Like 4 (Putative); C1orf169; Apolipoprotein B MRNA-Editing EnzymeCatalytic Polypeptide-Like 4; Chromosome 1 Open Reading Frame 169; Putative C->U-EditingEnzyme APOBEC-4; EC 3.5.4.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTEFCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRHIILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSGSHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSGQLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Formulation APOBEC4 protein solution (1mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.

Introduction

APOBEC4belongs to the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases,which convert cytidine to uridine. Further AID/APOBEC family members areimplicated in Mrna editing, somatic hypermutation and recombination ofimmunoglobulin genes, and innate immunity to retroviral infection. Among thediseases associated with APOBEC4 are systemic lupus erythematosus, and lupuserythematosus.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.