Anti-Mouse Galectin-9 Antibody (RG9-1)
目录号 : GC27253Anti-Mouse Galectin-9 Antibody (RG9-1) 是一种抗小鼠 Galectin-9 IgG2b 单克隆抗体。Anti-Mouse Galectin-9 Antibody (RG9-1) 通过增强 IFN-γ、TNF-α 和 IL-6 的分泌来促进炎症反应。Anti-Mouse Galectin-9 Antibody (RG9-1) 可以增加 CD8 T 细胞和 Treg 频率。Anti-Mouse Galectin-9 Antibody (RG9-1) 通过增加 CD4+ 和 CD8+ T 细胞浸润来缩短移植物存活时间。Anti-Mouse Galectin-9 Antibody (RG9-1) 可用于研究炎症疾病、癌症和异种移植，如缺血再灌注、结肠癌、乳腺癌和白血病。
Sample solution is provided at 25 µL, 10mM.
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Anti-Mouse Galectin-9 Antibody (RG9-1) is an anti-mouse Galectin-9 IgG2b monoclonal antibody. Anti-Mouse Galectin-9 Antibody (RG9-1) promotes inflammatory response by enhancing the secretion of IFN-γ, TNF-α, and IL-6. Anti-Mouse Galectin-9 Antibody (RG9-1) can increase CD8 T cell and Treg frequency. Anti-Mouse Galectin-9 Antibody (RG9-1) reduces graft survival time by increasing CD4+ and CD8+ T cell infiltration. Anti-Mouse Galectin-9 Antibody (RG9-1) can be used for researches on inflammation conditions, cancer and xenotransplantation such as ischemia-reperfusion, colon cancer, breast cancer and leukemia[1][2][3][4].
Anti-Mouse Galectin-9 Antibody (RG9-1) (10 μg，2 小时) 显著增加了同种异体反应性 T 细胞对角膜内皮细胞 (CECs) 的杀伤作用，并抑制了同种异体活性 CD4+ T 细胞的凋亡[1]。
Anti-Mouse Galectin-9 Antibody (RG9-1) (20 μg/mL) 显著增加了 Concanavalin A 刺激的脾脏 T 细胞中 IFN-γ 的产生[2]。
Anti-Mouse Galectin-9 Antibody (RG9-1) (20 μg/mL) 显著增加巨噬细胞和 T 细胞共培养系统中 TNF-α 和 IL-6 的分泌[2]。
Anti-Mouse Galectin-9 Antibody (RG9-1) 可以阻断 Gal-9/TIM-3 相互作用，减少 Jurkat T 细胞凋亡[3]。
GLPBIO has not independently confirmed the accuracy of these methods. They are for reference only.
References:
[1]. Shimmura-Tomita M, et al. Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts. PLoS One. 2013 May 7;8(5):e63620.
[2]. Uchida Y, et al. T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent manner. Gastroenterology. 2010 Dec;139(6):2195-206.
[3]. Yang R, et al. Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy. Nat Commun. 2021 Feb 5;12(1):832.
[4]. Llaó-Cid L, et al. Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL and identifies galectin-9 as an immunotherapy target. Nat Commun. 2025 Aug 7;16(1):7271.
| Cas No. | SDF | ||
| 分子式 | 分子量 | 150 kDa | |
| 溶解度 | 储存条件 | ||
| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
 |
1 mg | 5 mg | 10 mg |
| 1 mM | 6.7 μL | 33.3 μL | 66.7 μL |
| 5 mM | 1.3 μL | 6.7 μL | 13.3 μL |
| 10 mM | 0.7 μL | 3.3 μL | 6.7 μL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet