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Angiotensin

目录号 : GP21404

Angiotensin

Angiotensin Chemical Structure

规格 价格 库存 购买数量
1mg
¥1,820.00
5-10工作日
10mg
¥6,300.00
5-10工作日
200mg
¥28,000.00
5-10工作日

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Angiotensin contains a total of 8 amino acids having a molecular weight of 1031.2 Dalton and a molecular formula of C49H70N14O11.

Product Data

Purity Greater than 98.0% as determined by RP-HPLC. Source Synthetic.
Phycical Appearance Sterile Filtered white lyophilized powder. Shipping Condition Shipped at Room temp.
Synonyms Angiotensinogen; Serpin A8; ANHU; SERPINA8.
Amino Acid Sequence Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH.
Solubility It is recommended to reconstitute the lyophilized Angiotensin in sterile 18MΩ-cm H2O not less than 100 µg/ml or more than 10 mg/ml solutions.
Stability Lyophilized Angiotensin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Serpin A8 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.

Introduction

Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.

Stability

Lyophilized Angiotensin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution Serpin A8 should be stored at 4°C between 2-7 days and for future use below -18°C .Please prevent freeze-thaw cycles.