Home>>Angeli’s Salt
Angeli’s Salt 目录号 GC19428

Angeli’s salt is a classical nitroxyl (NO-) donor

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5mg
¥294.00
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10mg
¥599.00
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50mg
¥2,510.00
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100mg
¥4,400.00
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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 13826-64-7 SDF Download SDF
别名 Sodium α-oxyhyponitrite
化学名 disodium diazen-1-ium-1,2,2-triolate
Canonical SMILES N/A
分子式 Na2(ONNO2) 分子量 122.0
溶解度 H20: 50 mg/ml,PBS (pH 7.2): 50 mg/ml 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

Angeli’s salt is regarded as a classical nitroxyl (NO-) donor, but under certain conditions evolution of NO is also observed.1 It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2.3 minutes at 37°C (pH 7.4) to liberate 0.54 moles of NO per mole of parent compound.[1],[2]

Reference:
[1]. Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ∙NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects Journal of Medicinal Chemistry 34, 3242-3247 (1991).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996