Home>>Nucleotides/Nucleosides>>Adenylosuccinic Acid (ammonium salt)

Adenylosuccinic Acid (ammonium salt)

目录号 : GC49231

A purine nucleotide and an intermediate in the purine nucleotide cycle

规格 价格 库存 购买数量
10 mg
¥1,134.00
现货
25 mg
¥2,691.00
现货
50 mg
¥5,111.00
现货
100 mg
¥8,513.00
现货

Customer Review

Based on customer reviews.

电话:400-920-5774 Email: sales@glpbio.cn

Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

View current batch:

产品描述

Adenylosuccinic acid is a purine nucleotide and an intermediate in the purine nucleotide cycle.1 It is converted into AMP and fumarate by adenylosuccinate lyase in the cytosol. Adenylosuccinic acid (10 µM) inhibits calcium-induced activation of non-selective cation channels in isolated rat brown adipocytes in a patch-clamp assay.2 Adenylosuccinic acid (10 µM) increases glucose-induced insulin exocytosis in 832/13 INS-1 pancreatic β-cells.3 It induces contractions in isolated guinea pig uterus strips when used at a concentration of 100 µM.4

1.Waarde, A.Operation of the purine nucleotide cycle in animal tissuesBiol. Rev. Camb. Philos. Soc.63(2)259-298(1988) 2.Halonen, J., and Nedergaard, J.Adenosine 5’-monophosphate is a selective inhibitor of the brown adipocyte nonselective cation channelJ. Membr. Biol.188(1)183-197(2002) 3.Gooding, J.R., Jensen, M.W., Dai, X., et al.Adenylosuccinate is an insulin secretagogue derived from glucose-induced purine metabolismCell Rep.13(1)157-167(2015) 4.Nishida, Y., and Miyamoto, T.Contractile effect of succinylpurines on guinea pig uterusGen. Pharmacol.19(2)277-279(1988)

Chemical Properties

Cas No. N/A SDF
别名 N/A
化学名 N/A
Canonical SMILES [O-]P(OC[C@H]([C@@H](O)[C@H]1O)O[C@@]1([H])N2C=NC3=C(N[C@@H](CC([O-])=O)C([O-])=O)N=CN=C32)([O-])=O.[NH4+].[NH4+].[NH4+].[NH4+]
分子式 C14H14N5O11P·4NH4 分子量 531.4
溶解度 PBS (pH 7.2): 10 mg/ml 储存条件 -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置
  • 摩尔浓度计算器

  • 稀释计算器

质量
=
浓度
x
体积
x
分子量
 
 
 
*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算