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β-Casomorphin, bovine TFA Sale

(Synonyms: β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA) 目录号 : GC60391

β-casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) 是阿片 (opioid) 活性的多肽,与阿片受体结合的 IC50 值为 14 μM。

β-Casomorphin, bovine TFA Chemical Structure

规格 价格 库存 购买数量
5mg
¥720.00
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10mg
¥1,260.00
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50mg
¥3,120.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay[1].

β-Casomorphin, bovine TFA (0.1μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment[2].β-Casomorphin, bovine TFA (0.1μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels[2].β-Casomorphin, bovine TFA does not modify the expression of rMuc1, rMuc4, and rMuc5AC[2].β-Casomorphin, bovine TFA (0.1μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human)[2].

β-Casomorphin, bovine TFA (7.5×10-6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats[3].β-Casomorphin, bovine TFA (7.5×10-6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats[3].β-Casomorphin, bovine TFA (7.5×10-6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats[3].β-Casomorphin, bovine TFA (7.5×10-6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells[3]. Animal Model: Male Sprague-Dawley (SD) rats (200 g±10 g)[3]

[1]. Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28(17):1903-9. [2]. Zoghbi S, et al. β-casomorphin-7-7 regulates the secretion and expression of gastrointestinal mucins through a μ-opioid pathway. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1105-13. [3]. Zhang W, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472.

Chemical Properties

Cas No. SDF
别名 β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA
分子式 C43H56F3N7O11 分子量 903.94
溶解度 储存条件
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.1063 mL 5.5313 mL 11.0627 mL
5 mM 0.2213 mL 1.1063 mL 2.2125 mL
10 mM 0.1106 mL 0.5531 mL 1.1063 mL
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