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5-trans Latanoprost Sale

(Synonyms: 反式拉坦前列素) 目录号 : GC41094

An analytical standard

5-trans Latanoprost Chemical Structure

Cas No.:913258-34-1

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1mg
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5mg
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10mg
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50mg
¥25,268.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity of between 2-5% in most commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, 5-trans latanoprost's biological activity is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity, and on the intraocular hypotensive activity in particular, of 5-trans latanoprost.

Chemical Properties

Cas No. 913258-34-1 SDF
别名 反式拉坦前列素
Canonical SMILES O[C@@H]1[C@H](C/C=C/CCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
分子式 C26H40O5 分子量 432.6
溶解度 DMF: 100 mg/ml,DMSO: 50 mg/ml,Ethanol: Miscible,PBS (pH 7.2): 1.5 mg/ml 储存条件 Store at -20°C
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.3116 mL 11.558 mL 23.116 mL
5 mM 0.4623 mL 2.3116 mL 4.6232 mL
10 mM 0.2312 mL 1.1558 mL 2.3116 mL
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