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Varioxepine A Sale

目录号 : GC48502

A fungal metabolite

Varioxepine A Chemical Structure

Cas No.:1623451-72-8

规格 价格 库存 购买数量
250µg
¥2,141.00
现货
1mg
¥7,281.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Varioxepine A is a fungal metabolite originally isolated from P. variotii.1 It is active against the plant pathogenic fungus F. graminearum (MIC = 4 µg/ml).

1.Zhang, P., MÁndi, A., Li, X.-M., et al.Varioxepine A, a 3H-oxepine-containing alkaloid with a new oxa-cage from the marine algal-derived endophytic fungus Paecilomyces variotiiOrg. Lett.16(18)4834-4837(2014)

Chemical Properties

Cas No. 1623451-72-8 SDF
Canonical SMILES CC(C)C(NC1=O)=C2N=C(OC=CC=C3)[C@@]3(OC[C@H](C(C)(O4)C)O5)[C@]54N2[C@H]1CC6=CC=CC=C6
分子式 C26H29N3O5 分子量 463.5
溶解度 储存条件 -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.1575 mL 10.7875 mL 21.575 mL
5 mM 0.4315 mL 2.1575 mL 4.315 mL
10 mM 0.2157 mL 1.0787 mL 2.1575 mL
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Research Update

Varioxepine A, a 3H-oxepine-containing alkaloid with a new oxa-cage from the marine algal-derived endophytic fungus Paecilomyces variotii

Org Lett 2014 Sep 19;16(18):4834-7.PMID:25167167DOI:10.1021/ol502329k.

A new 3H-oxepine-containing alkaloid, Varioxepine A (1), characterized by a structurally unprecedented condensed 3,6,8-trioxabicyclo[3.2.1]octane motif, was isolated from the marine algal-derived endophytic fungus Paecilomyces variotii. Due to the low proton/carbon ratio, the unambiguous assignment of the planar structure and relative configuration was precluded by NMR experiments and solved by single crystal X-ray analysis. The absolute configuration was established by DFT conformational analysis and TDDFT-ECD calculations. Compound 1 inhibited plant pathogenic fungus Fusarium graminearum.