Home>>Trichlormethine (Tris(2-chloroethyl)amine)

Trichlormethine (Tris(2-chloroethyl)amine) Sale

(Synonyms: 三(2-氯乙基)胺) 目录号 : GC30432

Trichlormethine是一种化学的中间体。

Trichlormethine (Tris(2-chloroethyl)amine) Chemical Structure

Cas No.:555-77-1

规格 价格 库存 购买数量
100mg
¥446.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Trichloromethane is a solvent, as a chemical intermediate, and in pesticide formulations.

Chemical Properties

Cas No. 555-77-1 SDF
别名 三(2-氯乙基)胺
Canonical SMILES ClCCN(CCCl)CCCl
分子式 C6H12Cl3N 分子量 204.53
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 4.8893 mL 24.4463 mL 48.8926 mL
5 mM 0.9779 mL 4.8893 mL 9.7785 mL
10 mM 0.4889 mL 2.4446 mL 4.8893 mL
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Research Update

Extraction-spectrophotometric determination of tris(2-chloroethyl)amine using phthaleins

Procedures for the extraction-spectrophotometric determination of tris(2-chloroethyl)amine, an alkylating agent known as a drug as well as a chemical warfare agent (nitrogen mustard HN-3), with 7 acid-base indicators of a triphenylmethane lactone type, phthaleins, were developed. Representatives of phthaleins without an oxygen bridge (thymolphthalein, o-cresolphthalein, naphtholphthalein) and with an oxygen bridge (fluorescein, 2',7'-dichlorofluorescein, eosin B and eosin Y) were used. The methods were based on the formation of ion pair complexes. Chloroform was used as a non-polar solvent for an extraction. The conditions to determine were optimized for the optimal pH of the buffer and the concentration of a phthalein as a reagent. The dependence on the reaction time in a water phase and the stoichiometry of extraction products were studied. The detection limits and the limits of the determination of separate procedures and conditional extraction constants were determined. Comparison with the spectrophotometric method of the group determination of alkyl halides and acyl halides using alkaline ethanol-water solution of thymolphthalein, the so-called T-135 agent, was conducted. While studying the selectivity, the possible interference of bis(2-chloroethyl)sulphide and 3 nitrogen mustards in the proposed procedures were verified. Copyright ? 2016 John Wiley & Sons, Ltd.

Organic Chemical Attribution Signatures for the Sourcing of a Mustard Agent and Its Starting Materials

Chemical attribution signatures (CAS) are being investigated for the sourcing of chemical warfare (CW) agents and their starting materials that may be implicated in chemical attacks or CW proliferation. The work reported here demonstrates for the first time trace impurities from the synthesis of tris(2-chloroethyl)amine (HN3) that point to the reagent and the specific reagent stocks used in the synthesis of this CW agent. Thirty batches of HN3 were synthesized using different combinations of commercial stocks of triethanolamine (TEA), thionyl chloride, chloroform, and acetone. The HN3 batches and reagent stocks were then analyzed for impurities by gas chromatography/mass spectrometry. All the reagent stocks had impurity profiles that differentiated them from one another. This was demonstrated by building classification models with partial least-squares discriminant analysis (PLSDA) and obtaining average stock classification errors of 2.4, 2.8, 2.8, and 11% by cross-validation for chloroform (7 stocks), thionyl chloride (3 stocks), acetone (7 stocks), and TEA (3 stocks), respectively, and 0% for a validation set of chloroform samples. In addition, some reagent impurities indicative of reagent type were found in the HN3 batches that were originally present in the reagent stocks and presumably not altered during synthesis. More intriguing, impurities in HN3 batches that were apparently produced by side reactions of impurities unique to specific TEA and chloroform stocks, and thus indicative of their use, were observed.