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Tyrosine Kinase

  1. Cat.No. Product Name Information
  2. GC41183 α-Carotene α-Carotene is a precursor of vitamin A that has been found in various fruits and vegetables.
  3. GC38006 β-Hydroxyisovalerylshikonin Beta-hydroxyisovalerylshikonin 是一种从Lithospermium radix 中分离出的天然产物,是一种有效的 PTK 抑制剂, 对 EGFR 和 v-Src 受体作用的 IC50 分别为 0.7 μM 和 1 μM。Beta-hydroxyisovalerylshikonin 对多种肿瘤细胞系均有抑制作用,能高效诱导 NCI-H522 和 DMS114 细胞的死亡。
  4. GC41653 (±)16(17)-DiHDPA (±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid.
  5. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system.
  6. GC13944 (5Z)-7-Oxozeaenol

    TAK1 mitogen-activated protein kinase kinase kinase (MAPKKK) inhibitor

  7. GC17800 (E)-FeCP-oxindole VEGFR-2 inhibitor
  8. GC61807 (E/Z)-AG490

    (E/Z)-AG490((E/Z)-TyrphostinAG490)是(E)-AG490和(Z)-AG490的消旋体。(E)-AG490是一种酪氨酸激酶抑制剂,可抑制EGFR,Stat-3和JAK2/3。

  9. GC14729 (R)-Crizotinib C-MET/ALK inhibitor,potent and ATP-competitve
  10. GC19012 (R)-GNE-140

     A TRK kinase (TKI) inhibitor

  11. GC13136 (S)-Crizotinib Potent MTH1 inhibitor
  12. GC13344 (Z)-FeCP-oxindole VEGFR-2 inhibitor
  13. GC12172 1-Naphthyl PP1 Src family kinases inhibitor
  14. GC34119 1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) 1-NaphthylPP1(1-NA-PP1)盐酸盐是src家族抑制剂,对v-Src,c-Fyn,c-Abl,CDK2和CAMKII的IC50分别为1.0,0.6,0.6,18和22μM。
  15. GC11696 1-NM-PP1 Pp60c-src inhibitor
  16. GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine.
  17. GC35053 123C4 123C4 是一种有效、选择性的,竞争性受体酪氨酸激酶 EPHA4 激动剂,Ki 值为 0.65 μM.
  18. GC46474 18-Deoxyherboxidiene
  19. GC33087 2,4-Pyrimidinediamine with linker 2,4-Pyrimidinediaminewithlinker是专利WO2013055780A1(71页,intermediate2),激酶抑制剂,含linker结构。
  20. GC33519 2,5-Dihydroxybenzoic acid 2,5-Dihydroxybenzoicacid是苯甲酸的代谢物,也是纤维母细胞生长因子(fibroblastgrowthfactor)的强效抑制剂。
  21. GC10408 2-D08 Sumoylation inhibitor

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