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GSK-3

GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.

  1. Cat.No. Product Name Information
  2. GC13907 1-Azakenpaullone GSK-3β inhibitor,potent and selective,cell-permeable
  3. GC14306 3F8 GSK-3β inhibitor
  4. GC35162 5-Iodo-indirubin-3'-monoxime 5-Iodo-indirubin-3'-monoxime 是一种有效的 GSK-3β,CDK5/P25 和 CDK1/cyclin B 抑制剂,与 ATP 竞争性地结合酶的催化位点,IC50 值分别为 9,20 和 25 nM。
  5. GC39152 9-ING-41 9-ING-41 是一个有效的糖原合酶激酶 3 (GSK-3) 抑制剂。9-ING-41 通过靶向中心体和微管结合的 GSK-3β 诱导前期凋亡和细胞周期停滞。9-ING-41 具有抗肿瘤活性。
  6. GC10336 A 1070722 GSK-3 inhibitor
  7. GC15841 Alsterpaullone CDKs and GSK3β inhibitor
  8. GC15425 AR-A014418 GSK3β inhibitor, ATP-competitive and selective
  9. GC16568 AZD1080 GSK3βinhibitor
  10. GC14736 AZD2858 GSK-3 inhibitor,potent and selective
  11. GC10752 Bikinin GSK3 inhibitor and Brassinosteroid activator
  12. GC14233 BIO-acetoxime

    GSK-3α/β inhibitor

  13. GC38892 BIP-135 BIP-135 是一个高效、选择性的,ATP 竞争性的 GSK-3 抑制剂,对 GSK-3α 和 GSK-3β 作用的IC50 值分别为 16 nM 和 21 nM。BIP 135 具有神经保护作用。
  14. GC39181 BRD0705 BRD0705 是一种有效的,具有旁系选择性和口服活性的 GSK3α 抑制剂,IC50 为 66 nM,Kd 为 4.8 μM。 BRD0705 与 GSK3β (IC50 为 515 nM) 相比,对 GSK3α 的选择性更高 (8 倍)。BRD0705 可用于治疗急性髓细胞性白血病。
  15. GC15642 CHIR 99021 trihydrochloride glycogen synthase kinase 3 (GSK-3) inhibitor
  16. GC12176 CHIR-98014 GSK-3β inhibitor,selective and ATP-competitive
  17. GC16702 CHIR-99021 (CT99021) GSK-3 inhibitor, Cell-permeable, ATP-competitive
  18. GC17153 CHIR-99021 (CT99021) HCl GSK-3α/β inhibitor
  19. GC13176 CP21R7 GSK3β inhibitor
  20. GC17690 Cromolyn sodium Mast cell membrane stabilizer
  21. GC17457 FRATide GSK-3 inhibitor

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