PI3K/Akt/mTOR Signaling
- Akt(89)
- AMPK(53)
- CK2(8)
- DNA-PK(24)
- eNOS(2)
- GSK-3(43)
- MELK(5)
- mTOR(78)
- PI3K(164)
- PI4K(12)
- PDK-1(10)
- PIKfyve(2)
- PKB(1)
- S6 Kinase(9)
- Cat.No. Product Name Information
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GC17330
(+)-Usniacin
Naturally occurring dibenzofuran derivative
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GC34444
(R)-Nedisertib
(R)-Nedisertib((R)-M3814)是一种活性较弱的Nedisertib的R型异构体,对DNA-PK的IC50值为7-30nM。
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GC35037
1,3-Dicaffeoylquinic acid
1,3-Dicaffeoylquinic acid是咖啡酰奎宁酸衍生物,具有抗氧化活性和自由基清除活性。
-
GC13907
1-Azakenpaullone
GSK-3β inhibitor,potent and selective,cell-permeable
-
GC13006
10-DEBC hydrochloride
Akt inhibitor
-
GC35124
3α-Hydroxymogrol
3α-Hydroxymogrol 是从罗汉果中得到的三萜类化合物,为有效的 AMPK 激活剂,可增强 AMPK 的磷酸化水平。
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GC13992
3-Guanidinopropionic Acid
AMPK stimulator
-
GC10710
3-Methyladenine
Class III PI3K inhibitor
-
GC32767
3BDO
3BDO是一种新型mTOR激活剂,也能抑制自噬。
-
GC12078
3CAI
AKT inhibitor
-
GC16960
4,5,6,7-Tetrabromobenzimidazole
CK2 inhibitor
-
GC35162
5-Iodo-indirubin-3’-monoxime
5-Iodo-indirubin-3'-monoxime 是一种有效的 GSK-3β,CDK5/P25 和 CDK1/cyclin B 抑制剂,与 ATP 竞争性地结合酶的催化位点,IC50 值分别为 9,20 和 25 nM。
-
GN10093
6-gingerol
Extracted from Zingiber officinale Roscoe;Suitability:Methanol,ethanol,DMSO;Store the product in sealed,cool and dry condition
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GC31348
7-Methoxyisoflavone
7-Methoxyisoflavone是异黄酮衍生物,也是腺苷一磷酸激活的蛋白激酶(AMPK)的激活剂。
-
GC16157
740 Y-P
PI 3-kinase activator,cell permeable
-
GC39152
9-ING-41
9-ING-41 是一个有效的糖原合酶激酶 3 (GSK-3) 抑制剂。9-ING-41 通过靶向中心体和微管结合的 GSK-3β 诱导前期凋亡和细胞周期停滞。9-ING-41 具有抗肿瘤活性。
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GC10336
A 1070722
GSK-3 inhibitor
-
GC12502
A-443654
Akt inhibitor,potent and selective
-
GC11875
A-674563
Akt1/PKA/CDK2 inhibitor,potent and selective
-
GC35212
A-674563 hydrochloride
A-674563 hydrochloride 是具有选择性的高效 Akt1 抑制剂,其 Ki 值为 11 nM。