Transferase(转移酶)
Transferases are a collection of a large and diverse group of enzymes that specifically catalyze the transfer of one or more functional groups from one molecule (the donor) to another (the acceptor). A few transferases involved in this category include farnesyltransferase (FTase), diacylglycerol acyltransferase (DGAT) and catechol-O-methyltransferase (COMT). Ftase catalyzes the transfer of a farnesyl moiety to the cysteine terminal residue (the sulfhydryl cysteine of the CAAS motif)) of substrate proteins. DGAT catalyzes the final step of the triacylglycerol (TG) biosynthetic pathway, where diacylglycerol is esterified to produce TG. COMT catalyzes the methylation of catechol substrates utilizing S-adenosyl-L-methionine (SAM) as a methyl donor and generating O-methylated catechol and S-adenosyl-L-homocysteine.
Products for Transferase
- Cat.No. 产品名称 Information
- GP26181 ST6GALNAC5 Human ST6GALNAC5 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 316 amino acids (30-336a
- GP26157 GST S. Japonicum GST S
- GP26156 GST S. Japonicum, His GST S
- GP26140 CHST5 Human CHST5 Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 380 amino acids (27-395 a
- GP26139 CHST3 Human CHST3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 450 amino acids (39-479
- GC12981 OU749 Inhibitor of γ-glutamyl transferase
- GC12912 BCATc Inhibitor 2 A selective BCATc inhibitor
- GC17780 FTase Inhibitor II Ftase inhibitor
- GC10905 Amodiaquine dihydrochloride dihydrate A prodrug form of N-desethyl amodiaquine
- GC10265 Manumycin A A farnesyltransferase inhibitor with antitumor activity
- GC16310 FTI 277 HCl FTI 277 HCl 是法尼基转移酶 (FTase) 的抑制剂;一种高效的 Ras CAAX 肽模拟物,可拮抗 H-和 K-Ras 致癌信号传导。
- GC11884 GPP 78 hydrochloride Inhibitor of Nampt
- GC16129 LY 78335 phenylethanolamine-N-methyltransferase (PNMT) inhibitor
- GC17046 Tris DBA N-myristoyltransferase-1 (NMT-1) inhibitor
- GC12449 SKF 91488 dihydrochloride histamine N-methyltransferase inhibitor
- GC11524 Cystamine dihydrochloride An inhibitor of tissue transglutaminase
- GC16612 GGsTop GGsTop (Nahlsgen) 是一种有效、无毒、高度选择性和不可逆的 γ-谷氨酰转肽酶 (GGT) 抑制剂,对人 GGT 的 Ki 为 170 μM。
- GC10106 OR-486 A potent COMT inhibitor
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GC16738
Tunicamycin Mixture
An antimicrobial and inhibitor of glycosylation
- GC10170 LB42708 A potent farnesyltransferase inhibitor
- GC15274 PF-04620110 A potent, bioavailable inhibitor of DGAT-1
- GC17921 Tolcapone A reversible COMT inhibitor
- GC15614 A922500 A diacylglycerol acyltransferase 1 inhibitor
- GC14308 FK866 (APO866) Inhibitor of nicotinamide phosphoribosyltransferase
- GC10330 Lonafarnib A farnesyltransferase inhibitor with antitumor activity
- GC15442 Tipifarnib (Zarnestra) A farnesyltransferase inhibitor with antitumor activity