Metabolism
- PPAR(120)
- 5-alpha Reductase(7)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(7)
- Aminopeptidase(9)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(21)
- CETP(12)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(22)
- Dehydrogenase(36)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(9)
- Enolase(2)
- FAAH(35)
- Factor Xa(16)
- Ferroptosis(107)
- Folate Analogue(2)
- Glucokinase(12)
- HLE(1)
- HMG-CoA Reductase(27)
- HSP(70)
- IDO(34)
- KRAS-PDEδ(3)
- Lipid Metabolism(16)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(4)
- P450(106)
- PDE(163)
- Phospholipase(58)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(14)
- SGLT(28)
- TPH(4)
- Transferase(21)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(0)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(1)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(0)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(10)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(76)
- Pyruvate kinase(5)
- Others(4)
- MGL(1)
- Galactosidase(1)
- 12-Lipoxygenase(1)
- Cat.No. Product Name Information
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GC45239
δ4-Abiraterone
δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone.
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GC15975
α-Estradiol
Endogenous estrogen receptor ligand
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GC14406
(±)-Acetylcarnitine chloride
weak cholinergic agonist; intermediates in lipid metabolism
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GC15834
(±)-Decanoylcarnitine chloride
intermediate in lipid metabolism
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GC17351
(±)-Hexanoylcarnitine chloride
important intermediates in lipid metabolism
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GC16427
(±)-Lauroylcarnitine chloride
important intermediates in lipid metabolism
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GC10056
(±)-Myristoylcarnitine chloride
cholinergic agonist; important intermediates in lipid metabolism
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GC13909
(±)-Octanoylcarnitine chloride
homolog of acetylcarnitine chloride
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GC12551
(±)-Propionylcarnitine chloride
homolog of acetylcarnitine chloride
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GC12404
(+)-Ketoconazole
Potent inhibitor of cytochrome P450c17
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GC30424
(-)-Cephaeline dihydrochloride (NSC 32944)
(-)-Cephaelinedihydrochloride是Cephaelinedihydrochloride的一种对映异构体。Cephaelinedihydrochloride是选择性的CYP2D6抑制剂,IC50为121μM。
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GC16081
(-)-epicatechin
inducer of pancreatic β-cell regeneration
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GC14049
(-)-Epigallocatechin gallate (EGCG)
Antioxidant, antiangiogenic and antitumor agent
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GC14520
(-)-p-Bromotetramisole Oxalate
ALP inhibitor, potent and non-specific
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GC13751
(3S,5S)-Atorvastatin (sodium salt)
negetive control of Atorvastatin, HMG-CoA reductase inhibitor
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GC34980
(E)-Ferulic acid
(E)-Ferulic acid 是阿魏酸 (Ferulic acid) 的异构体,阿魏酸是芳香族化合物,在植物细胞壁中丰富。 (E)-Ferulic acid 引起 β-连环蛋白 (β-catenin) 的磷酸化,导致蛋白酶体降解,增加促凋亡因子 Bax 的表达并降低促存活因子存活蛋白的表达。(E)-Ferulic acid 可以有效去除活性氧 (ROS) 和抑制脂质过氧化。(E)-Ferulic acid 在人肺癌细胞系 H1299 中发挥抗增殖和抗迁移作用。
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GA11210
(H-Cys-OH)2
(H-Cys-OH)2
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GC34984
(R)-(-)-Rolipram
(R)-(-)-Rolipram是cAMP-特异的PDE4抑制剂,IC50为220nM。在抑制PDE4膜结合实验中其抑制性高于(+)-rolipram 2.5倍。
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GC14486
(S)-Mephenytoin
substrate of the cytochrome P450 (CYP) isoform CYP2C19
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GC17913
1-Deazaadenosine
adenosine deaminase inhibitor