Membrane Transporter/Ion Channel
- AMPAR(58)
- ATPase(71)
- Calcium Channel(284)
- Cannabinoid Transporters(7)
- CFTR(27)
- Chloride Channels(14)
- GABA Receptor(216)
- Gardos Channel(1)
- Glucose Transporters(5)
- Glutamate (EAAT) Transporters(19)
- Glycine Receptors(2)
- GlyT(16)
- GTPase(19)
- Kv1.3(1)
- ICB(2)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(2)
- Monoamine transporter(14)
- Monocarboxylate Transporters(10)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(15)
- NKCC(7)
- NMDA Receptor(83)
- Nucleoside Transporters(4)
- Pannexin-1(2)
- P2X purinergic receptor(62)
- P-gp(10)
- Proton Pump(51)
- Potassium Channel(253)
- Sodium Channel(164)
- TRP Channel(134)
- TRPV1(10)
- URAT1(5)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(22)
- CRAC Channel(12)
- EAAT2(6)
- HCN Channel(4)
- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(27)
- P-glycoprotein(44)
- iGluR(141)
- nAChR(85)
- VDAC(2)
- Aquaporins(1)
- Piezo Channels(1)
- Cat.No. Product Name Information
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GC38677
(-)-α-Pinene
(-)-α-Pinene 是一种单萜类化合物,通过在 BZD 结合位点作为部分调节剂与 GABAA-苯二氮卓 (BZD) 受体直接结合,显示出增强睡眠的特性。
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GC49097
α-Conotoxin AuIB (trifluoroacetate salt)
A conotoxin and an antagonist of α3β4 subunit-containing nAChRs
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GC49140
α-Conotoxin ImI (trifluoroacetate salt)
A conotoxin and an antagonist of α7 nAChRs
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GC63269
α-Conotoxin PIA TFA
α-Conotoxin PIA TFA 是一种烟碱乙酰胆碱受体 (nAChR) 拮抗剂,靶向包含 α6 和 α3 亚基的 nAChR。α-Conotoxin PIA 具有研究帕金森氏症和精神分裂症的潜力。
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GC63723
α-Conotoxin PnIA TFA
α-Conotoxin PnIA TFA 是一种有效的选择性哺乳动物 α7nAChR 拮抗剂,具有研究神经性疼痛和阿尔茨海默氏病等神经系统疾病的潜力。
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GC10873
α-Spinasterol
TRPV1 antagonist
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GC63615
α-Thujone
α-Thujone 是一种从西方金钟柏精油中分离出来的单萜,具有有效的抗肿瘤活性。α-Thujone 是 GABAA 受体的可逆调节剂,在抑制 GABA 诱导的电流时,α-Thujone 的 IC50 为 21 μM。α-Thujone 诱导 ROS 依赖性细胞毒性,还诱导细胞凋亡 (apoptosis ) 和自噬 (autophagy)。α-Thujone 具有抗伤害,杀虫和驱虫活性,并且很容易穿透血脑屏障。
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GC48998
β-Defensin-1 (human) (trifluoroacetate salt)
An antimicrobial peptide
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GC38010
γ-Aminobutyric acid
γ-Aminobutyric acid (4-Aminobutyric acid) 是成年哺乳动物大脑中主要的抑制性神经递质,能够与离子移变 GABA 受体 (GABAA) 受体和促代谢受体 (GABAB) 受体结合发挥作用。
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GC48313
γ-Lindane
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GC15513
ω-Agatoxin IVA
P-type calcium channels blocker
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GC12608
ω-Agatoxin TK
CaV2.1 P/Q-type calcium channels blocker
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GC13886
ω-Conotoxin GVIA
blocker of N-type calcium channels
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GC18070
ω-Conotoxin MVIIC
wide spectrum blocker of N, P and Q type calcium channels
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GC31248
β-Amino Acid Imagabalin Hydrochloride (PD-0332334)
β-AminoAcidImagabalinHydrochloride(PD-0332334)是电压依赖性钙离子(calciumchannel)通道的α2δ亚基的配体
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GC11449
β-CCB
benzodiazepine receptor ligand
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GC18033
γDGG
glutamate receptor antagonist
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GC62067
ω-Conotoxin GVIA TFA
ω-Conotoxin GVIA TFA 是一种 N 型钙通道 (Ca2+ channel) 抑制剂。
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GA24016
ω-Conotoxin MVIIA
ω-Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitive Ca²? channels in neurons. The peptide has been used to identify different Ca²? channel subtypes in amphibian brain.
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GC49296
τ-Fluvalinate
A pyrethroid acaricide
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GC14410
(±)-Epibatidine
nicotinic agonist
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GC11138
(±)-HIP-A
excitatory amino acid transporter (EAAT) blocker
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GC13735
(±)-HIP-B
excitatory amino acid transporter (EAAT) blocker
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GC45985
(±)-Indoxacarb
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GC14834
(±)-Nipecotic acid
GABA uptake inhibitor
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GC41676
(±)-Nornicotine
(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist.
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GC49482
(±)-Nornicotine-d4
An internal standard for the quantification of (±)-nornicotine
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GC41677
(±)-SDZ-201 106
(±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels.
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GC11982
(±)-threo-3-Methylglutamic acid
glutamate transport blocker
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GC40466
(±)11(12)-EET
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.
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GC40434
(±)16-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
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GC40270
(±)5(6)-DiHET
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.
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GC40438
(±)5(6)-EET
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.
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GN10612
(+)- Praeruptorin C
Extracted from Peucedanum praeruptorum Dunn roots;Store the product in sealed, cool and dry condition
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GN10745
(+)-Bicuculline
GABAA receptor antagonist,competitve and classical
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GC34954
(+)-Borneol
(+)-Borneol (d-Borneol) 是用于中药镇痛和麻醉的天然双环单萜,增强 GABA 受体活性的 EC50 值为248 μM。
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GC30933
(+)-Kavain
(+)-Kavain是从卡瓦胡椒(Pipermethysticum)中提取的一种主要的卡瓦内酯,具有抗惊厥作用,通过电压依赖性的Na+和Ca2+通道相互作用,减弱血管平滑肌的收缩。Kavain能与α4β2δGABAA受体结合,加强GABA的功效。Kavain是一种治疗炎症疾病的药物,其抗炎作用已被广泛研究。
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GC40808
(+)-Menthol
(+)-Menthol is a monoterpene alcohol that has been found in Cannabis and has antifungal activity.
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GC16616
(+)-MK 801
Potent NMDA antagonist
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GC11025
(+)-MK 801 Maleate
Potent NMDA antagonist
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GC32130
(+)-SJ733 (SJ000557733)
(+)-SJ733是临床上治疗疟疾的候选物,也是一个Na+-ATPasePfATP4抑制剂。
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GC34959
(+)-Sparteine
(+)-Sparteine 是一种天然生物碱,作为一种神经节阻滞剂。在神经细胞中,(+)-Sparteine 竞争性地抑制烟碱型乙酰胆碱受体 (nACh receptor) 活性。
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GC31084
(-)-(S)-B-973B
(-)-(S)-B-973B为一种有效的α7nAChR别构激动剂和正别构调节剂,具有镇痛作用。
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GC10065
(-)-Bicuculline methiodide
GABAA receptor antagonist
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GC16857
(-)-Bicuculline methobromide
GABAA antagonist
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GC15636
(-)-Bicuculline methochloride
GABAA antagonist
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GC13430
(-)-Blebbistatin
Non muscle myosin II ATPase inhibitor
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GC63940
(-)-Denudatin B
(-)-Denudatin B 具有抗血小板作用,通过电压门控和受体调控的Ca2+通道抑制Ca2+内流,从而放松血管平滑肌。(-)-Denudatin B 通过抑制胶原蛋白和凝血酶诱导的磷酸肌苷分解,在高浓度下具有非特异性的抗血小板作用。
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GC14157
(-)-Lobeline hydrochloride
nicotinic receptor partial agonist
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GC34951
(-)-Menthol
(-)-Menthol 是薄荷油的关键成分,(-)-Menthol 结合并激活瞬瞬时受体电位 M8 (TRPM8),TRPM8 是 Ca2+-可渗透的非选择性阳离子通道,最终增加 [Ca2+]i。 具有抗肿瘤活性。