Membrane Transporter/Ion Channel

Cat.No. Product Name Information

GC38677 (-)-α-Pinene (-)-α-Pinene 是一种单萜类化合物，通过在 BZD 结合位点作为部分调节剂与 GABAA-苯二氮卓 (BZD) 受体直接结合，显示出增强睡眠的特性。

GC49097 α-Conotoxin AuIB (trifluoroacetate salt) A conotoxin and an antagonist of α3β4 subunit-containing nAChRs

GC49140 α-Conotoxin ImI (trifluoroacetate salt) A conotoxin and an antagonist of α7 nAChRs

GC63269 α-Conotoxin PIA TFA α-Conotoxin PIA TFA 是一种烟碱乙酰胆碱受体 (nAChR) 拮抗剂，靶向包含 α6 和 α3 亚基的 nAChR。α-Conotoxin PIA 具有研究帕金森氏症和精神分裂症的潜力。

GC63723 α-Conotoxin PnIA TFA α-Conotoxin PnIA TFA 是一种有效的选择性哺乳动物 α7nAChR 拮抗剂，具有研究神经性疼痛和阿尔茨海默氏病等神经系统疾病的潜力。

GC10873 α-Spinasterol TRPV1 antagonist

GC63615 α-Thujone α-Thujone 是一种从西方金钟柏精油中分离出来的单萜，具有有效的抗肿瘤活性。α-Thujone 是 GABAA 受体的可逆调节剂，在抑制 GABA 诱导的电流时，α-Thujone 的 IC50 为 21 μM。α-Thujone 诱导 ROS 依赖性细胞毒性，还诱导细胞凋亡 (apoptosis ) 和自噬 (autophagy)。α-Thujone 具有抗伤害，杀虫和驱虫活性，并且很容易穿透血脑屏障。

GC48998 β-Defensin-1 (human) (trifluoroacetate salt) An antimicrobial peptide

GC38010 γ-Aminobutyric acid

γ-Aminobutyric acid (4-Aminobutyric acid) 是成年哺乳动物大脑中主要的抑制性神经递质，能够与离子移变 GABA 受体 (GABAA) 受体和促代谢受体 (GABAB) 受体结合发挥作用。

GC48313 γ-Lindane

GC15513 ω-Agatoxin IVA P-type calcium channels blocker

GC12608 ω-Agatoxin TK CaV2.1 P/Q-type calcium channels blocker

GC13886 ω-Conotoxin GVIA

blocker of N-type calcium channels

GC18070 ω-Conotoxin MVIIC wide spectrum blocker of N, P and Q type calcium channels

GC31248 β-Amino Acid Imagabalin Hydrochloride (PD-0332334) β-AminoAcidImagabalinHydrochloride(PD-0332334)是电压依赖性钙离子(calciumchannel)通道的α2δ亚基的配体

GC11449 β-CCB benzodiazepine receptor ligand

GC18033 γDGG glutamate receptor antagonist

GC62067 ω-Conotoxin GVIA TFA

ω-Conotoxin GVIA TFA 是一种 N 型钙通道 (Ca2+ channel) 抑制剂。

GA24016 ω-Conotoxin MVIIA ω-Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitive Ca²? channels in neurons. The peptide has been used to identify different Ca²? channel subtypes in amphibian brain.

GC49296 τ-Fluvalinate A pyrethroid acaricide

GC14410 (±)-Epibatidine nicotinic agonist

GC11138 (±)-HIP-A excitatory amino acid transporter (EAAT) blocker

GC13735 (±)-HIP-B excitatory amino acid transporter (EAAT) blocker

GC45985 (±)-Indoxacarb

GC14834 (±)-Nipecotic acid GABA uptake inhibitor

GC41676 (±)-Nornicotine (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist.

GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine

GC41677 (±)-SDZ-201 106 (±)-SDZ-201 106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels.

GC11982 (±)-threo-3-Methylglutamic acid glutamate transport blocker

GC40466 (±)11(12)-EET

(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.

GC40434 (±)16-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.

GC40270 (±)5(6)-DiHET

5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.

GC40438 (±)5(6)-EET 5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.

GN10612 (+)- Praeruptorin C Extracted from Peucedanum praeruptorum Dunn roots;Store the product in sealed, cool and dry condition

GN10745 (+)-Bicuculline GABAA receptor antagonist,competitve and classical

GC34954 (+)-Borneol (+)-Borneol (d-Borneol) 是用于中药镇痛和麻醉的天然双环单萜，增强 GABA 受体活性的 EC50 值为248 μM。

GC30933 (+)-Kavain (+)-Kavain是从卡瓦胡椒(Pipermethysticum)中提取的一种主要的卡瓦内酯，具有抗惊厥作用，通过电压依赖性的Na+和Ca2+通道相互作用，减弱血管平滑肌的收缩。Kavain能与α4β2δGABAA受体结合，加强GABA的功效。Kavain是一种治疗炎症疾病的药物，其抗炎作用已被广泛研究。