Chemokine Receptors(趋化因子受体)

Cat.No. 产品名称 Information

GC50742 Chemerin-9, Mouse Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM)

GC50711 ML 339 Potent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM)

GC50655 AZ 10397767 Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin-induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells

GC50351 KRH 3955 hydrochloride Highly potent CXCR4 antagonist; inhibits HIV-1 replication

GC50229 VUF 11222 High affinity non-peptide CXCR3 agonist

GC35673 Chemerin-9 149-157 Chemerin-9 (149-157)，是位于chemerin-9 149-157位的多肽 (YFPGQFAFS(157)，与加工后的chemerin 的 C端相对应，保留了全蛋白绝大部分活性，与对chemerinR的激动作用有关。

GC13458 SB 265610 A selective CXCR2 inverse agonist

GC14317 BMS CCR2 22 BMS CCR2 22 是一种有效、特异性和高亲和力的 CC 型趋化因子受体 2 (CCR2) 拮抗剂，具有出色的结合亲和力（结合 IC50 为 5.1 nM）和有效的功能拮抗作用（钙通量 IC50 为 18 nM，趋化性 IC50 为 1 nM）。

GC14554 J 113863 J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂，对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。

GC14551 VUF 11207 fumarate ACKR3 (CXCR7) chemokine receptor agonist

GC10432 IT1t dihydrochloride A CXCR4 antagonist

GC11946 SB 297006 A selective antagonist of CCR3

GC17834 Teijin compound 1 A CCR2b antagonist

GC15183 SB 328437 A CCR3 antagonist

GC11161 C 021 dihydrochloride C 021 dihydrochloride 是一种有效的 CC 趋化因子受体 4 (CCR4) 拮抗剂。

GC14519 BX 471 A selective CCR1 antagonist

GC13299 BX 513 hydrochloride Selective CCR1 antagonist

GC15045 (±)-AMG 487 A CXCR3 antagonist

GC11316 UCB 35625 chemokine CCR1 and CCR3 receptor antagonist

GC11327 ZK 756326 A non-peptide agonist of CCR8

GC11026 RS 102895 hydrochloride A chemokine receptor CCR2 antagonist

GC13360 CTCE 9908 CTCE 9908 是一种有效的选择性 CXCR4 拮抗剂。 CTCE 9908 在表达 CXCR4 的卵巢癌细胞中诱导有丝分裂灾难、细胞毒性并抑制迁移。

GC17040 DAPTA A CCR5 receptor antagonist

GC13774 FC 131 An inhibitor of CXCR4 activation

GC17122 TC 14012

TC14012, a serum-stable derivative of T140, is a selective and peptidomimetic CXCR4 antagonist with an IC₅₀ of 19.