Home>>Pyropheophorbide a methyl ester

Pyropheophorbide a methyl ester

目录号 GC49860

规格 价格 库存 购买数量
5 mg
¥868.00
现货
10 mg
¥1,652.00
现货
25 mg
¥3,262.00
现货

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Sample solution is provided at 25 µL, 10mM.

质量管理

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产品描述

Pyropheophorbide a methyl ester is a photosensitizer and a derivative of chlorophyll a .1 It induces cell death in RIF-1 cells when used in combination with photodynamic therapy (PDT) at concentrations of 0.06 and 1 µM. Pyropheophorbide a methyl ester localizes to cell membranes and induces IL-1 receptor internalization and NF-κB activation following light exposure in HCT116 cells.2

1.Chen, Y., Zheng, X., Dobhal, M.P., et al.Methyl pyropheophorbide-a analogues: Potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacyJ. Med. Chem.48(11)3692-3695(2005) 2.Matroule, J.-Y., Bonizzi, G., MorliÈre, P., et al.Pyropheophorbide-a methyl ester-mediated photosensitization activates transcription factor NF-κB through the interleukin-1 receptor-dependent signaling pathwayJ. Biol. Chem.274(5)2988-3000(1999)

Chemical Properties

Cas No. 6453-67-4 SDF Download SDF
别名 N/A
化学名 N/A
Canonical SMILES O=C1CC(C2=C1C(C)=C(C=C3C(CC)=C(C)C(C=C4C(C=C)=C(C)C(N4)=C5)=N3)N2)=C6[C@@H](CCC(OC)=O)[C@H](C)C5=N6
分子式 C34H36N4O3 分子量 548.7
溶解度 Chloroform: slightly soluble,Methanol: slightly soluble when heated 储存条件 -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

动物体内配方计算器 (澄清溶液)

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