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Pentaacetylquercetin 目录号 GC40189

A quercetin derivative with diverse biological activities

规格 价格 库存 购买数量
10mg
¥575.00
现货
50mg
¥1,875.00
现货
100mg
¥3,160.00
现货
500mg
¥14,364.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 1064-06-8 SDF Download SDF
别名 N/A
化学名 N/A
Canonical SMILES CC(OC1=CC=C(C2=C(OC(C)=O)C(C(C(OC(C)=O)=CC(OC(C)=O)=C3)=C3O2)=O)C=C1OC(C)=O)=O
分子式 C25H20O12 分子量 512.4
溶解度 DMF: 30 mg/mL,DMSO: 30 mg/mL,DMSO:PBS(pH 7.2) (1:4): 1 mg/mL,Ethanol: 2 mg/mL 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).