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Myelopeptide-2 (MP-2) 目录号 GP10114

Peptide used for restoring human T lymphocytes

规格 价格 库存 购买数量
1mg
¥305.00
现货
5mg
¥893.00
现货
10mg
¥1,565.00
现货
25mg
¥2,069.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. N/A SDF
别名 H2N-Leu-Val-Val-Tyr-Pro-Trp-OH
化学名 N/A
Canonical SMILES N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(O)C=C1)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CC(C=CC=C4)=C4N3)C(O)=O)=O)=O)=O)=O)=O
分子式 C41H57N7O8 分子量 775.93
溶解度 ≥ 77.5mg/mL in DMSO 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

Myelopeptide-2 (MP-2) (C41H57N7O8), with the sequence Leu-Val-Val-Tyr-Pro-Trp, is originally isolated from the supernatant of porcine bone marrow cell culture, and is able to restore the mitogen responsiveness of human T lymphocytes inhibited by conditioned medium from HL-60 leukemia cells or measles virus. The MP-2 recovery effect is connected with its influence on the CD3 and CD4 antigen expression on T lymphocytes. Research results also suggest that the MP-2 involvement in regulatory processes is directed to the maintenance of immune homeostasis. This peptide is perspective to be applied in antitumor and antivirus therapy.

References:
1. Mikhailova AA, Belevskaya RG, Kalyuzhnaya M, Fonina LA, Liashenko VA, Petrov RV. Myelopeptide-2 recovers interleukin-2 synthesis and interleukin-2 receptor expression in human T lymphocytes depressed by tumor products or measles virus.