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Moguisteine Sale

(Synonyms: 莫吉司坦; BBR-2173) 目录号 : GC16326

An antitussive agent

Moguisteine Chemical Structure

Cas No.:119637-67-1

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥378.00
现货
100mg
¥473.00
现货
250mg
¥819.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

Moguisteine(BBR-2173) is a novel peripheral non-narcotic antitussive drug.Target: OthersMoguisteine is a novel peripheral nonnarcotic antitussive agent that has proved to be as active as codeine in several experimental models of induced cough in guinea-pigs and dogs. It acts neither through the opiate receptors nor on the cough centre, and its action is possibly mediated by the interaction with rapidly adapting irritant receptors along the tracheobronchial tree. In controlled clinical trials, moguisteine has been shown to be safe and to effectively reduce cough associated with such respiratory disorders as acute upper respiratory tract infection, chronic bronchitis, pulmonary fibrosis and malignancies [1, 2].

References:
[1]. Gallico, L., et al., Moguisteine: a novel peripheral non-narcotic antitussive drug. Br J Pharmacol, 1994. 112(3): p. 795-800.
[2]. Gallico, L., et al., Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo. Eur Respir J, 1996. 9(3): p. 478-85.

Chemical Properties

Cas No. 119637-67-1 SDF
别名 莫吉司坦; BBR-2173
化学名 ethyl 3-[2-[(2-methoxyphenoxy)methyl]-1,3-thiazolidin-3-yl]-3-oxopropanoate
Canonical SMILES CCOC(=O)CC(=O)N1CCSC1COC2=CC=CC=C2OC
分子式 C16H21NO5S 分子量 339.41
溶解度 ≥ 16.95mg/mL in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.9463 mL 14.7314 mL 29.4629 mL
5 mM 0.5893 mL 2.9463 mL 5.8926 mL
10 mM 0.2946 mL 1.4731 mL 2.9463 mL
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