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Misoprostol Sale

(Synonyms: 米索前列醇,SC-29333) 目录号 : GC16074

A PGE1 analog and agonist of EP2 and EP3 receptors

Misoprostol Chemical Structure

Cas No.:59122-46-2

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥441.00
现货
5mg
¥378.00
现货

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Sample solution is provided at 25 µL, 10mM.

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产品描述

Misoprostol(SC29333) is a synthetic prostaglandin E1 (PGE1) analog that is used to prevent gastric ulcers, to treat missed miscarriage, to induce labor, and to induce abortion.Target: Prostaglandin ReceptorMisoprostol is a synthetic analog of natural prostaglandin E1. It produces a dose-related inhibition of gastric acid and pepsin secretion, and enhances mucosal resistance to injury. It is an effective anti-ulcer agent and also has oxytocic properties. Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. Administration of misoprostol to EP3+/+ and EP3-/- mice showed similar levels of infarct rescue, indicating that misoprostol protection was not mediated through the EP3 receptor. Taken together, these findings suggest a novel function for misoprostol as a protective agent in cerebral ischemia acting via the PGE(2) EP2 and/or EP4 receptors [1, 2].

References:
[1]. Li, J., et al., Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia. Neurosci Lett, 2008. 438(2): p. 210-5.
[2]. http://www.drugbank.ca/drugs/DB00929

Chemical Properties

Cas No. 59122-46-2 SDF
别名 米索前列醇,SC-29333
化学名 methyl 7-((1R,2R,3R)-3-hydroxy-2-((E)-4-hydroxy-4-methyloct-1-en-1-yl)-5-oxocyclopentyl)heptanoate
Canonical SMILES CCCCC(C/C([H])=C([H])/[C@]1([H])[C@@](C(C[C@@]1([H])O)=O)([H])CCCCCCC(OC)=O)(O)C
分子式 C22H38O5 分子量 382.53
溶解度 ≥ 11.05mg/mL in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.6142 mL 13.0709 mL 26.1417 mL
5 mM 0.5228 mL 2.6142 mL 5.2283 mL
10 mM 0.2614 mL 1.3071 mL 2.6142 mL
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