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Oxychlororaphine Sale

(Synonyms: 吩嗪-1-甲酰胺,phenazine-1-carboxamide) 目录号 : GC45538

A microbial metabolite with diverse biological activities

Oxychlororaphine Chemical Structure

Cas No.:550-89-0

规格 价格 库存 购买数量
5mg
¥550.00
现货
10mg
¥1,044.00
现货
25mg
¥2,187.00
现货
100mg
¥5,760.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Oxychlororaphine is a phenazine microbial metabolite that has been found in a variety of bacteria and has anticancer, antibacterial, and antifungal activities.1,2 It is cytotoxic to A549, HeLa, and SW480 cancer cells (IC50s = 32-40 μM).1 Oxychlororaphine halts the cell cycle at the G1 phase and induces apoptosis in A549 cells. It is active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi when used at concentrations ranging from 12.5 to 50 ppm.2

References
1. Ali, H.M., El-Shikh, M.S., Salem, M.Z.M., et al. Isolation of bioactive phenazine-1-carboxamide from the soil bacterium Pantoea agglomerans and study of its anticancer potency on different cancer cell lines. J. AOAC Int. 99(5), 1233-1239 (2016).
2. Sierra, G., and Veringa, H.A. Effect of oxy-chlororaphin on the growth in vitro of Streptomyces species and some pathogenic fungi. Nature 182(4630), 265 (1958).

Chemical Properties

Cas No. 550-89-0 SDF
别名 吩嗪-1-甲酰胺,phenazine-1-carboxamide
Canonical SMILES NC(C1=CC=CC2=C1N=C3C(C=CC=C3)=N2)=O
分子式 C13H9N3O 分子量 223.2
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 4.4803 mL 22.4014 mL 44.8029 mL
5 mM 0.8961 mL 4.4803 mL 8.9606 mL
10 mM 0.448 mL 2.2401 mL 4.4803 mL
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