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Nicotinamide riboside chloride 目录号 GC36738

规格 价格 库存 购买数量
10mM*1mL in Water
¥495.00
现货
100mg
¥450.00
现货
500mg
¥1,860.00
现货

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Sample solution is provided at 25 µL, 10mM.

Nicotinamide riboside chloride Dilution Calculator

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Nicotinamide riboside chloride Molarity Calculator

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Chemical Properties

Cas No. 23111-00-4 SDF Download SDF
别名 N/A
化学名 N/A
Canonical SMILES NC(C1=C[N+]([C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)=CC=C1)=O.[Cl-]
分子式 C11H15ClN2O5 分子量 290.7
溶解度 H2O : 250 mg/mL (859.99 mM; Need ultrasonic) 储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

产品描述

Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride which is a nicotinamide adenine dinucleotide (NAD[+]) precursor vitamin. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements[1]. SIRT1 SIRT3

Nicotinamide riboside chloride (0.5 nM; 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1]. Western Blot Analysis[1] Cell Line: HEK293T cells

Chronic Nicotinamide riboside chloride (p.o.; 400 mg/kg/day; for 16 weeks) supplementation increases plasma and intracellular NAD[+] content in a tissue-specific manner[1]. Animal Model: 10-week-old C57Bl/6J mice[1]

[1]. CantÓ C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6;15(6):838-47.