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(-)-Menthol Sale

(Synonyms: L-薄荷醇) 目录号 : GC34951

A monoterpene with diverse biological activities

(-)-Menthol Chemical Structure

Cas No.:2216-51-5

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10mM (in 1mL DMSO)
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产品描述

(–)-Menthol is a monoterpene that has been found in cornmint oil and has diverse biological activities.1 It inhibits acetylcholinesterase (AChE; Ki = 1.25 mM for the bovine enzyme).2 (–)-Menthol (1.6 mM) decreases expression of the genes encoding topoisomerase I, IIα, and Iiβ in, and cell viability of, SNU-5 gastric cancer cells.3 It is active against the plant pathogenic bacteria A. tumefaciens and E. carotovora (MICs = 2.5 and 4 ?g/ml, respectively).4 (–)-Menthol (3-10 mg/kg) reduces acetic acid-induced writhing and increases latency to paw licking in a hot plate test in mice.5

1.Kamatou, G.P., Vermaak, I., Viljoen, A.M., et al.Menthol: A simple monoterpene with remarkable biological propertiesPhytochemistry9615-25(2013) 2.Miyazawa, M., Watanabe, H., and Kameoka, H.Inhibition of acetylcholinesterase activity by monoterpenoids with a p-menthane skeletonJ. Agric. Food Chem.45(3)677-679(1997) 3.Lin, J.P., Lu, H.F., Lee, J.H., et al.(-)-Menthol inhibits DNA topoisomerases I, II α and β and promotes NF-? B expression in human gastric cancer SNU-5 cellsAnticancer Res.25(3B)2069-2074(2005) 4.Rasoul, M.A.A., Marei, G.I.K., and Abdelgaleil, S.A.M.Evaluation of antibacterial properties and biochemical effects of monoterpenes on plant pathogenic bacteriaAfr. J. Microbiol. Res.6(15)3667-3672(2012) 5.Galeotti, N., Di Cesare Mannelli, L., Mazzanti, G., et al.Menthol: A natural analgesic compoundNeurosci. Lett.322(3)145-148(2002)

Chemical Properties

Cas No. 2216-51-5 SDF
别名 L-薄荷醇
Canonical SMILES O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1
分子式 C10H20O 分子量 156.27
溶解度 DMSO: 100 mg/mL (639.92 mM) 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 6.3992 mL 31.9959 mL 63.9918 mL
5 mM 1.2798 mL 6.3992 mL 12.7984 mL
10 mM 0.6399 mL 3.1996 mL 6.3992 mL
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