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Docosanoic Acid-d4 Sale

(Synonyms: 二十二烷酸) 目录号 : GC47254

An internal standard for the quantification of docosanoic acid

Docosanoic Acid-d4 Chemical Structure

Cas No.:1208430-53-8

规格 价格 库存 购买数量
500 μg
¥823.00
现货
1 mg
¥1,559.00
现货
5 mg
¥5,345.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

Docosanoic acid-d4 is intended for use as an internal standard for the quantification of docosanoic acid by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.1,2 It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).3 Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase Λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.4 Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.5 Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.

1.Dean, L.L., and Sanders, T.H.Hexacosanoic acid and other very long-chain fatty acids in peanut seed oilPlant Genet. Resour.7(3)252-256(2009) 2.SÁnchez-Machado, D.I., LÓpez-Cervantes, J., NÚÑez-GastÉlum, J.A., et al.Effect of the refining process on Moringa oleifera seed oil qualityFood Chem.18753-57(2015) 3.Iijima, H., Kasai, N., Chiku, H., et al.The inhibitory action of long-chain fatty acids on the DNA binding activity of p53Lipids41(6)521-527(2006) 4.Yonezawa, Y., Hada, T., Uryu, K., et al.Inhibitory action of C22-fatty acids on DNA polymerases and DNA topoisomerasesInt. J. Mol. Med.18(4)583-588(2006) 5.Serviddio, G., Bellanti, F., Villani, R., et al.Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approachRedox Biol.9296-305(2016)

Chemical Properties

Cas No. 1208430-53-8 SDF
别名 二十二烷酸
Canonical SMILES CCCCCCCCCCCCCCCCCC([2H])([2H])CC([2H])([2H])CC(O)=O
分子式 C22H40D4O2 分子量 344.6
溶解度 DMF: 3 mg/ml,DMF:PBS (pH 7.2): 0.5 mg/ml 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.9019 mL 14.5096 mL 29.0192 mL
5 mM 0.5804 mL 2.9019 mL 5.8038 mL
10 mM 0.2902 mL 1.451 mL 2.9019 mL
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