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DETA NONOate 目录号 GC18259

A NO donor

规格 价格 库存 购买数量
10mg
¥377.00
现货
50mg
¥1,417.00
现货
100mg
¥2,457.00
现货
500mg
¥8,489.00
现货

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 146724-94-9 SDF Download SDF
别名 N/A
化学名 (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate
Canonical SMILES [NH3+]CCN(N(N=O)[O-])CCN
分子式 C4H13N5O2 分子量 163.2
溶解度 aqueous buffers: >100 mg/ml 储存条件 Store at -80°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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产品描述

DETA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.[1],[2]

Reference:

[1]. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines The Journal of Organic Chemistry 58, 1472-1476 (1993).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996).