Chlorophyllin Mixture
目录号 : GC47081
A mixture of chlorin-based compounds
Cas No.:85536-03-4
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Chlorophyllin mixture is a mixture of chlorin-based compounds.1 Formulations containing chlorophyllin have been used as food coloring agents.
1.Tumolo, T., and Lanfer-Marquez, U.M.Copper chlorophyllin: A food colorant with bioactive properties•Food Res. Int.46(2)451-459(2012)
| Cas No. | 85536-03-4 | SDF | |
| Canonical SMILES | [O-]C(CC1=C2[N-]3[Cu+2]([N](C4=C5)=C(C(CC)=C4C)C=C3C(C)=C2C([O-])=O)([N-]6C5=C7C=C)[N](C([C@H]8C)=CC6=C7C)=C1[C@H]8CCC([O-])=O)=O.[Na+].[Na+].[Na+] | ||
| 分子式 | C34H31CuN4O6.3Na (for Copper Chlorin e6 (sodium salt)) | 分子量 | 724.2 |
| 溶解度 | PBS (pH 7.2): 0.3mg/mL | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.3808 mL | 6.9042 mL | 13.8083 mL |
| 5 mM | 0.2762 mL | 1.3808 mL | 2.7617 mL |
| 10 mM | 0.1381 mL | 0.6904 mL | 1.3808 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Photooxidative bleaching of chlorophyllin
Free Radic Res 1999 Dec;31 Suppl:S97-105.PMID:10694047DOI:10.1080/10715769900301381.
Chlorophyllin, a water-soluble, copper-containing porphyrin, can be bleached rapidly in the light or slowly in the dark in a reaction which is oxygen dependent. Both the photo and the dark bleaching reactions are temperature dependent. Cyclic voltammetry measurements show that the copper in the bleached and nonbleached state remains in the +2 redox state and could be readily reduced. This would imply that there is no net oxidative change to the copper during the bleaching process. FT-IR absorption spectroscopy showed vibrations characteristic of a vinyl functionality disappeared upon bleaching. Aqueous solutions of chlorophyllin were not dialyzable through dialysis tubing of molecular weight cut-off, 6000-8000 molecular weight, indicative of an aggregate chlorophyllin micelle. Analysis of products by high performance liquid chromatography showed that the Chlorophyllin Mixture was more complex than originally anticipated and that two components were lost from the mixture upon photobleaching. One compound that is preferentially lost upon photobleaching has been identified by mass spectral analysis as Cu(II) chlorin e6.