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Lomefloxacin HCl Sale

(Synonyms: 盐酸洛美沙星; SC47111A hydrochloride) 目录号 : GC11657

A broad-spectrum fluoroquinolone antibiotic

Lomefloxacin HCl Chemical Structure

Cas No.:98079-52-8

规格 价格 库存 购买数量
10mM (in 1mL DMSO)
¥347.00
现货
50mg
¥473.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Lomefloxacin hydrochloride is a fluoroquinolone antibiotic.Target: AntibacterialLomefloxacin hydrochloride is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited [1].

References:
[1]. http://www.drugbank.ca/drugs/DB00978

Chemical Properties

Cas No. 98079-52-8 SDF
别名 盐酸洛美沙星; SC47111A hydrochloride
化学名 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride
Canonical SMILES CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl
分子式 C17H19F2N3O3.HCl 分子量 387.81
溶解度 ≥ 6.3mg/mL in Water with gentle warming; 1mg/mL in DMSO (Need ultrasonic) 储存条件 4°C, protect from light
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 2.5786 mL 12.8929 mL 25.7858 mL
5 mM 0.5157 mL 2.5786 mL 5.1572 mL
10 mM 0.2579 mL 1.2893 mL 2.5786 mL
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