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Moxifloxacin Sale

(Synonyms: 莫西沙星) 目录号 : GC11992

莫西沙星是一种具有口服活性的 8-甲氧基喹诺酮类抗菌药物,用于治疗急性细菌性鼻窦炎、慢性支气管炎的急性细菌性加重和社区获得性肺炎。

Moxifloxacin Chemical Structure

Cas No.:151096-09-2

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50mg
¥357.00
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200mg
¥1,155.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

Moxifloxacin is an orally bio-available, broad spectrum bacterial gyrase-inhibiting fluoroquinolone antibiotic [1].

Moxifloxacin at 50 μg/mL has been reported to induce a significant reduction of viable cells. A remarkable anti-proliferative activity of moxifloxacin has been proved in the concentrations between 50 and 1500 μg/mL. Moreover, moxifloxacin could lead to signs of cellular damage which were seen like binucleation in a dose-dependent manner [2].

Rats intravenously injected with moxifloxacin at 100 mg/kg have shown the increase of Serum glucose and serum epinephrine concentrations as well as the release of histamine. However, moxifloxacin at 75 mg/kg did not show any effects on serum epinephrine, glucose or histamine concentrations increase [3].

References:
[1] Iatropoulos MJ1, Jeffrey AM, Enzmann HG, von Keutz E, Schlueter G, Williams GM. Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic. Exp Toxicol Pathol. 2001 Oct;53(5):345-57.
[2] Sobolewska B1, Hofmann J, Spitzer MS, Bartz-Schmidt KU, Szurman P, Yoeruek E. Antiproliferative and cytotoxic properties of moxifloxacin on rat retinal ganglion cells. Curr Eye Res. 2013 Jun;38(6):662-9.
[3] Ishiwata Y1, Takahashi Y, Nagata M, Yasuhara M. Effects of moxifloxacin on serum glucose concentrations in rats. Biol Pharm Bull. 2013;36(4):686-90.

Chemical Properties

Cas No. 151096-09-2 SDF
别名 莫西沙星
化学名 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid
Canonical SMILES COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
分子式 C21H24FN3O4 分子量 401.43
溶解度 ≥ 50.8 mg/mL in DMSO with gentle warming, ≥ 11.62 mg/mL in EtOH with ultrasonic and warming, ≥ 25.6 mg/mL in Water with ultrasonic and warming 储存条件 Store at -20°C
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1 mg 5 mg 10 mg
1 mM 2.4911 mL 12.4555 mL 24.9109 mL
5 mM 0.4982 mL 2.4911 mL 4.9822 mL
10 mM 0.2491 mL 1.2455 mL 2.4911 mL
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