Home>>C18 Ganglioside GM2-d3 (d18:1/18:0-d3) (ammonium salt)

C18 Ganglioside GM2-d3 (d18:1/18:0-d3) (ammonium salt) Sale

(Synonyms: C18 GM2-d3, N-omega-CD3-Octadecanoyl monosialoganglioside GM2, Monosialoganglioside GM2-d3, N-Stearoyl Monosialoganglioside GM2-d3) 目录号 : GC46993

A neuropeptide with diverse biological activities

C18 Ganglioside GM2-d3 (d18:1/18:0-d3) (ammonium salt) Chemical Structure

规格 价格 库存 购买数量
250 μg
¥8,395.00
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Sample solution is provided at 25 µL, 10mM.

产品文档

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产品描述

C18 Ganglioside GM2-d3 is intended for use as an internal standard for the quantification of ganglioside GM2 by GC- or LC-MS. C18 Ganglioside GM2 is a monosialylated ganglioside found in the mammalian brain where it is localized to the cell membrane.1 It accumulates in Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively.2 Ganglioside GM2 disrupts the function of immune cells and, when used at a concentration of 25 µM, increases migration and invasion of SK-RC-45 cells with no effect on proliferation.3 [Matreya, LLC. Catalog No. 2051]

1.Schnaar, R.L.Gangliosides of the vertebrate nervous systemJ. Mol. Biol.428(16)3325-3336(2016) 2.Baek, R.C., Martin, D.R., Cox, N.R., et al.Comparative analysis of brain lipids in mice, cats, and humans with Sandhoff diseaseLipids44(3)197-205(2009) 3.Kundu, M., Mahata, B., Banerjee, A., et al.Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathwayBiochim. Biophys. Acta.1863(7 Pt A)1472-1489(2016)

Chemical Properties

Cas No. N/A SDF
别名 C18 GM2-d3, N-omega-CD3-Octadecanoyl monosialoganglioside GM2, Monosialoganglioside GM2-d3, N-Stearoyl Monosialoganglioside GM2-d3
Canonical SMILES OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@@]2([H])[C@@H]([C@@]([C@H]([C@H](O2)CO)O[C@]3([H])O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)O)O)CO)([H])O[C@]4(C([O-])=O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@@H]([C@H](O)CO)O)O4)O)O[C@H]1OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O.[NH4+]
分子式 C67H117D3N3O26.NH4 分子量 1404.7
溶解度 Chloroform:Methanol:Water (2:1:0.1): Soluble 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.7119 mL 3.5595 mL 7.119 mL
5 mM 0.1424 mL 0.7119 mL 1.4238 mL
10 mM 0.0712 mL 0.3559 mL 0.7119 mL
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