Home>>Peptides>>β-Amyloid 29-40 (Amyloid beta-protein(29-40))

β-Amyloid 29-40 (Amyloid beta-protein(29-40)) Sale

(Synonyms: 淀粉Β-蛋白,Amyloid beta-protein(29-40)) 目录号 : GC31137

β-Amyloid 29-40 (Amyloid beta-protein(29-40)) 是 Amyloid-β 的一个片段;肽。

β-Amyloid 29-40 (Amyloid beta-protein(29-40)) Chemical Structure

Cas No.:184865-04-1

规格 价格 库存 购买数量
1mg
¥714.00
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5mg
¥2,142.00
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10mg
¥3,481.00
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Sample solution is provided at 25 µL, 10mM.

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产品描述

β-Amyloid (29-40) is a fragment of Amyloid-β peptide.

β-Amyloid (29-40) is a fragment of Amyloid-β peptide, unsoluble in water, acetonitrile or in a mixture of both in different ratios. Cationic arginine residues is introduced at β-Amyloid (29-40) C-terminus to solubilize β-Amyloid (29-40) and introduce cationicity in this Aβ stretch to enable it to interact with the negatively charged membrane of bacteria. β-Amyloid (29-40) variants shows antimicrobial effect[1]. Single chain variable fragments (scFv's) binds the 17-28 region of Abeta and effectively inhibits in vitro aggregation of Abeta, but binding the carboxyl-terminal region of β-Amyloid (29-40) does not inhibit aggregation[2].

[1]. Harioudh MK, et al. A short non-cytotoxic antimicrobial peptide designed from Aβ29-40 adopts a nanostructure and shows in vivo anti-endotoxin activity. Chem Commun (Camb). 2017 Dec 5;53(97):13079-13082. [2]. Liu R, et al. Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity. Biochemistry. 2004 Jun 8;43(22):6959-67.

Chemical Properties

Cas No. 184865-04-1 SDF
别名 淀粉Β-蛋白,Amyloid beta-protein(29-40)
Canonical SMILES Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
分子式 C49H88N12O13S 分子量 1085.36
溶解度 Soluble in DMSO 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
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溶解性数据

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1 mg 5 mg 10 mg
1 mM 0.9214 mL 4.6068 mL 9.2135 mL
5 mM 0.1843 mL 0.9214 mL 1.8427 mL
10 mM 0.0921 mL 0.4607 mL 0.9214 mL
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