| 6-NBDG 目录号 GC18870 |
Sample solution is provided at 25 µL, 10mM.
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| Cas No. | 108708-22-1 | SDF | Download SDF |
| 别名 | N/A | ||
| 化学名 | 6-deoxy-6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose | ||
| Canonical SMILES | O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]1CNC2=CC=C([N+]([O-])=O)C3=NON=C23 | ||
| 分子式 | C12H14N4O8 | 分子量 | 342.3 |
| 溶解度 | Soluble in DMSO | 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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6-NBDG is a non-hydrolyzable fluorescent glucose analog that is used to monitor glucose uptake and transport in living cells. 6-NBDG has been validated as a probe for the glucose transporter GLUT1 in cells. The fluorophore NBD displays excitation/emission maxima of 465/535 nm.
References:
1. Hansen, T.V.A., Hansen, M., Nejsum, P., et al. Glucose absorption by the bacillary band of Trichuris muris PLoS Negl. Trop. Dis. 10(9), e0004971 (2016).
2. Wang, M.S., Luo, Z., and Nitin, N. Rapid assessment of drug response in cancer cells using microwell array and molecular imaging Anal. Bioanal. Chem. 406(17), 4195-4206 (2014).
3. Zaman, R.T., Kosuge, H., Pratx, G., et al. Fiber-optic system for dual-modality imaging of glucose probes 18F-FDG and 6-NBDG in atherosclerotic plaques PLoS One 9(9), e108108 (2014).
4. Barros, L.F., Bittner, C.X., Loaiza, A., et al. Kinetic validation of 6-NBDG as a probe for the glucose transporter GLUT1 in astrocytes J. Neurochem. 109(Suppl 1), 94-100 (2009).