| 4-hydroxy Nonenal 目录号 GC42410 |
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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Purity = 95.00%
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- SDS (Safety Data Sheet)
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4-hydroxy Nonenal Dilution Calculator
4-hydroxy Nonenal Molarity Calculator
| Cas No. | 75899-68-2 | SDF | Download SDF |
| 别名 | 4-HNE | ||
| 化学名 | (±)-4-hydroxy-2E-nonenal | ||
| Canonical SMILES | CCCCCC(O)\C=C\C=O | ||
| 分子式 | C9H16O2 | 分子量 | 156.2 |
| 溶解度 | 50mg/mL in DMSO or DMF | 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid.[1],[2] 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation.[2] It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity.[1],[2],[3] 4-hydroxy Nonenal inhibits pro-oxidant-induced Ca2+ release from mitochondria at 10-50 µM.[2]
Reference:
[1]. Pryor, W.A., and Porter, N.A. Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids Free Radical Biology & Medicine 8, 541-543 (1990).
[2]. Esterbauer, H., Schaur, R.J., and Zoliner, H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde, and related aldehydes Free Radical Biology & Medicine 11, 81-128 (1991).
[3]. Sodum, R.S., and Chung, F.L. 1,N2-ethenodeoxyguanosine as a potential marker for DNA adduct formation by trans-4-hydroxy-2-nonenal Cancer Research 48, 320-323 (1988).