(1R,3S)-3-Aminomethyl-cyclopentanol
(Synonyms: (1R,3S)-3-(氨基甲基)环戊烷-1-醇) 目录号 : GC41687(1R,3S)-3-Aminomethyl-cyclopentanol is a synthetic intermediate useful for pharmaceutical synthesis.
Cas No.:1110772-09-2
Sample solution is provided at 25 µL, 10mM.
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(1R,3S)-3-Aminomethyl-cyclopentanol is a synthetic intermediate useful for pharmaceutical synthesis.
Cas No. | 1110772-09-2 | SDF | |
别名 | (1R,3S)-3-(氨基甲基)环戊烷-1-醇 | ||
Canonical SMILES | O[C@H]1C[C@@H](CN)CC1 | ||
分子式 | C6H13NO | 分子量 | 115.2 |
溶解度 | Soluble in DMSO | 储存条件 | Store at -20°C |
General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。 为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。 |
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Shipping Condition | 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。 |
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 8.6806 mL | 43.4028 mL | 86.8056 mL |
5 mM | 1.7361 mL | 8.6806 mL | 17.3611 mL |
10 mM | 0.8681 mL | 4.3403 mL | 8.6806 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
[(1R,3S)-3-(1,3-Dithian-2-yl)-2,2-dimethyl-cyclo-prop-yl]diphenyl-methanol
Acta Crystallogr Sect E Struct Rep Online 2009 May 7;65(Pt 6):o1230.PMID:21583098DOI:10.1107/S1600536809016079.
In the title compound, C(22)H(26)OS(2), prepared from (-)-1R-cis-caronaldehyde, the 1,3-dithiane ring adopts a chair conformation. An intra-molecular O-H⋯S hydrogen bond influences the mol-ecular conformation. In the crystal, weak inter-molecular C-H⋯S and C-H⋯O hydrogen bonds link the mol-ecules into chains propagating along [010].
(1R,3S,4R,4aS,7R,7aS,10R,12aR)-3-Azido-4,7,10-trimethyl-1,10-epidioxy-per-hydropyrano[4,3-j][1,2]benzodiox-epine
Acta Crystallogr Sect E Struct Rep Online 2010 Jun 26;66(Pt 7):o1839.PMID:21588040DOI:10.1107/S1600536810024566.
In the title compound, C(15)H(23)N(3)O(4), the six-membered pyran, cyclo-hexane and trioxane rings adopt chair, chair and boat conformations, respectively, while the seven-membered rings adopt distorted boat and very distorted chair conformations. In the crystal, adjacent mol-ecules are connected by weak C-H⋯N and C-H⋯O inter-actions.
(1R,3S,8R)-3,7,7,10-Tetra-methyl-tri-cyclo-[6.4.0.0(1,3)]dodec-9-en-11-one
Acta Crystallogr Sect E Struct Rep Online 2013 Dec 21;70(Pt 1):o81-2.PMID:24527013DOI:10.1107/S1600536813034041.
The absolute configuration of the title compound, C16H24O, has been deduced from the chemical pathway. The six-membered ring has a roughly half-chair conformation with the quaternary C atom as the flap. The seven-membered ring displays a chair conformation. In the crystal, there is a weak C-H⋯O hydrogen bond between the methyl-ene group of the cyclo-propane ring and the carbonyl group of a screw-axis-related mol-ecule, which builds up a zigzag-like chain along the b-axis direction.
(1R,3S)-3-Hydroxy-meth-yl-N-isopropyl-2,2-dimethyl-cyclo-propane-carboxamide
Acta Crystallogr Sect E Struct Rep Online 2009 Dec 12;66(Pt 1):o118.PMID:21580007DOI:10.1107/S1600536809051538.
The asymmetric unit of the title compound, C(10)H(19)NO(2), prepared from (-)-1R-cis-caronaldehyde, contains two independent mol-ecules. In the crystal structure, inter-molecular O-H⋯O and O-H⋯N hydrogen bonds form an extensive three-dimensional hydrogen-bonding network.
[(1R,3S)-6,7-Dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinolin-3-yl]methanol 2.33-hydrate
Acta Crystallogr Sect E Struct Rep Online 2011 Feb 23;67(Pt 3):o700.PMID:21522445DOI:10.1107/S1600536811006052.
The title compound, C(18)H(21)NO(3)·2.33H(2)O, is the fourth reported member in a series of (1R,3S)-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline derivatives used in catalysis as ligands (or their precursors). The N-heterocycle in the structure adopts a half-chair conformation. The dihedral angle between the benzene rings is 77.29 (13)°. There are three ill-resolved water molecules of crystallization in the structure (one of them rotationally disordered about a threefold axis) involved in short contacts probably due to hydrogen bonding.